Protein Info for Echvi_0819 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Predicted signal-transduction protein containing cAMP-binding and CBS domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 173 PF00027: cNMP_binding" amino acids 29 to 114 (86 residues), 28 bits, see alignment E=8.6e-11

Best Hits

KEGG orthology group: None (inferred from 53% identity to psn:Pedsa_0520)

Predicted SEED Role

"cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FVQ6 at UniProt or InterPro

Protein Sequence (173 amino acids)

>Echvi_0819 Predicted signal-transduction protein containing cAMP-binding and CBS domains (Echinicola vietnamensis KMM 6221, DSM 17526)
MEIDEILNKTYPMSKESKRLVTENIAEVYCRKNYIIISADRIERNIYFIKTGIARTFAKI
GDQEITFAFGKEGDTVASLNSFIANQKGYEYIELLEDSVLYELNSKCLQGLFNESIEIAN
WGRRFAENELIKTEKRLISRQSGTASERYEELLIKFPDYQKGSIGAYCLLFRY