Protein Info for Echvi_0801 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: Cytochrome c-type biogenesis protein CcmE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 141 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details signal peptide" amino acids 25 to 27 (3 residues), see Phobius details PF03100: CcmE" amino acids 37 to 130 (94 residues), 53.6 bits, see alignment E=1.2e-18

Best Hits

KEGG orthology group: K02197, cytochrome c-type biogenesis protein CcmE (inferred from 59% identity to mtt:Ftrac_2484)

Predicted SEED Role

"Cytochrome c-type biogenesis protein CcmE, heme chaperone" in subsystem Biogenesis of c-type cytochromes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FWF8 at UniProt or InterPro

Protein Sequence (141 amino acids)

>Echvi_0801 Cytochrome c-type biogenesis protein CcmE (Echinicola vietnamensis KMM 6221, DSM 17526)
MKKGHIIGLGIIAVAIVIIITSIGDASSYESFSTAKEMAMNGDDDPIHVVGQLKKDSRGS
VTGLEISEDKTSFTFSMIDNDGTEQQVYYNEPVPADFTRSEQVVVIGAYKNDQVFVADKI
LMKCPSKYQDNEFREVASSKK