Protein Info for Echvi_0791 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Zn-dependent dipeptidase, microsomal dipeptidase homolog
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01273, membrane dipeptidase [EC: 3.4.13.19] (inferred from 58% identity to hhy:Halhy_4130)Predicted SEED Role
"Zn-dependent dipeptidase"
MetaCyc Pathways
- leukotriene biosynthesis (2/6 steps found)
- gliotoxin biosynthesis (2/9 steps found)
- peptido-conjugates in tissue regeneration biosynthesis (6/17 steps found)
- arachidonate metabolites biosynthesis (3/74 steps found)
Isozymes
Compare fitness of predicted isozymes for: 3.4.13.19
Use Curated BLAST to search for 3.4.13.19
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0FWE8 at UniProt or InterPro
Protein Sequence (417 amino acids)
>Echvi_0791 Zn-dependent dipeptidase, microsomal dipeptidase homolog (Echinicola vietnamensis KMM 6221, DSM 17526) MKKTILPKAGIFLLLTALSCSEKPVQEDYTALSEEARLEAAKKIAQETIMVDGHVDLPYR MKVGGFTLQREVLDVSERTDGGNFDFPRAKEGGLDAPFMSIYLPARYQQTGGAKTLADSL ILMTKRLAETWPEKFAMAYSPDDIEANFKAGKVSLPMGMENGAGIEDDINNVAYFHEKGI RYITLTHGKDNLIGDSSYDTSRTHGGLTTFGEQVVKEMNRVGIMVDISHVSDDTFYDVME LTDVPVIASHSSCRKYTPGFERNMDDEMIKLLGKENGVIMINFGGSFIDGNYNERTAEVR EHIVNWLAENELSRTDSTAKAYIEKYVADHNVFPDVSLVADHIDHVVELAGIDHVGFGSD FDGVGDSLPNGLKDVSMYPNLIAELLKRGYSREDVEKICYKNVFRVWRAVEAAAQNS