Protein Info for Echvi_0778 in Echinicola vietnamensis KMM 6221, DSM 17526
Annotation: Beta-glucosidase-related glycosidases
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01188, beta-glucosidase [EC: 3.2.1.21] (inferred from 50% identity to chu:CHU_0013)Predicted SEED Role
"Beta-hexosaminidase (EC 3.2.1.52)" in subsystem Chitin and N-acetylglucosamine utilization or N-Acetyl-Galactosamine and Galactosamine Utilization (EC 3.2.1.52)
MetaCyc Pathways
- cellulose degradation II (fungi) (2/3 steps found)
- neolinustatin bioactivation (2/3 steps found)
- linamarin degradation (1/2 steps found)
- lotaustralin degradation (1/2 steps found)
- linustatin bioactivation (2/4 steps found)
- chitin degradation II (Vibrio) (3/6 steps found)
- coumarin biosynthesis (via 2-coumarate) (2/5 steps found)
- chitin degradation III (Serratia) (3/7 steps found)
- peptidoglycan recycling I (8/14 steps found)
- α-tomatine degradation (1/6 steps found)
- peptidoglycan recycling II (3/10 steps found)
- firefly bioluminescence (2/14 steps found)
KEGG Metabolic Maps
- Aminosugars metabolism
- Cyanoamino acid metabolism
- Glycosaminoglycan degradation
- Glycosphingolipid biosynthesis - ganglio series
- Glycosphingolipid biosynthesis - globo series
- Nucleotide sugars metabolism
- Other glycan degradation
- Phenylpropanoid biosynthesis
- Starch and sucrose metabolism
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.21, 3.2.1.52
Use Curated BLAST to search for 3.2.1.21 or 3.2.1.52
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See L0FVL9 at UniProt or InterPro
Protein Sequence (990 amino acids)
>Echvi_0778 Beta-glucosidase-related glycosidases (Echinicola vietnamensis KMM 6221, DSM 17526) MNQKVWRVPFVLMLIGGMVFFQLSFGFEKESIENPGDPLRTRDYVAQKKWVDSVFNSLTF EERLGQLFMVAAYSNRGEAHKQRIAKLIREEQLGGLIFFQGGPVRQAHLTNYYQSITKTP LLIAMDAEWGVSMRLDSVIQFPKQMTLGAIRDDELIYDMGTEIARQFKELGMHVNFAPVV DVNSNPNNPVIGYRAFGEQKEKVAKKAVAYMKGLQDHGVMANAKHFPGHGDTDSDSHYTT PVIQNSKDQIQDIDLYPYRQLIKENLMSVMVAHLHIPSLGTTAGKPTTLTPAVVNDLLKK DMGFEGLVFTDALNMKGVSSLHEPGEVDLLALLAGNDVLLYAEDVPKSKRLILQAVEEGR ISKAQIDGRVRKILKAKYWAGLNRPQHVNTDHLVERLSTYETAALVERLYAGSMTMVSNK GNFLPIRNQDLLKMASITLGNGGETFQHYLDKFGKFTHYRLPRNSNNQSYRALEQNLNDF NTIVVGITDVSNSPRRNFGIKADDMYFIKNLSEKYNVITVLFGNAYAAKYLEGLPNVLVA YEENEYTEKLAPQVIFGARGVNGALPATVSAGLPAGISVPFESKDRLGYSYPENEGMDSR TLNNIDEVVNRAIRRKSTPGACVLVAKDGKVVFERGYGHLDYKKGQTVTPETVYDLASIT KVMATTQTVMFLESRGLLDMEDPVSKYLPELIGTNKADLKLNDIMAHEAGLAPWIPHYTK TIHSGKWDPIFYHRTKGSGYSIQVAKGMYGMDALPDSVWKWTVESPLRRKSSSKGYDYKY SDLTMYIMQKVVERILNQPMDAFLEQNFYHPLGLYTLTYRPLEKYDMDRIAPTENDVVFR HELVRGHVHDPGAAMYGGVAGHAGLFGTAHDLAVMMQMMLQHGKYGGINLLDAKTVKEFT KRQSDQSRRGWGWDKPDPEPGEGGPAGELASKNSFGHTGFTGTAVWADPDENLIYVFLSN RVYPNASNNSLLRDNVRTDIQDIIYRAIRK