Protein Info for Echvi_0566 in Echinicola vietnamensis KMM 6221, DSM 17526

Updated annotation (from data): TonB-dependent receptor for glucose (SusC-like)
Rationale: Specifically important for utilization of D-glucose.
Original annotation: TonB-linked outer membrane protein, SusC/RagA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1079 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 33 to 1079 (1047 residues), 883.8 bits, see alignment E=2e-269 PF13620: CarboxypepD_reg" amino acids 34 to 104 (71 residues), 41.6 bits, see alignment 2.5e-14 PF13715: CarbopepD_reg_2" amino acids 35 to 116 (82 residues), 73.6 bits, see alignment 2.1e-24 PF07715: Plug" amino acids 123 to 228 (106 residues), 75.6 bits, see alignment E=8.2e-25 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 204 to 234 (31 residues), 58.1 bits, see alignment (E = 5.6e-20) PF00593: TonB_dep_Rec_b-barrel" amino acids 485 to 1038 (554 residues), 55.9 bits, see alignment E=1.4e-18

Best Hits

KEGG orthology group: None (inferred from 63% identity to sli:Slin_5798)

Predicted SEED Role

"SusC, outer membrane protein involved in starch binding"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FSD7 at UniProt or InterPro

Protein Sequence (1079 amino acids)

>Echvi_0566 TonB-dependent receptor for glucose (SusC-like) (Echinicola vietnamensis KMM 6221, DSM 17526)
MAKLLSNFKLGVALLCLMASTLIPLSFAFGQSIQVTGKVTDADNGESIPGASISQKGTTK
GTITDLDGNYSIEVSEGATLVFSFIGYSTQEVPVSGQSTIDVSMKTDIKGLEEVVVVGYG
TQKKQDLTGAVSVVKMEEMTQQPSPQLTSQLQGRVSGVTITGSGQPGQAPEIKIRGVNTF
GNNTPLFIVDGVPTPNINDINPNDVETMQVLKDAGAASIYGSRAANGVIIVTTKKGRGDV
KVNYNMYIGSQQVQGGNPWDILSSQEMADLKFMALRNTNPGGTINDDQYGSGPDPVLPNY
IAPVGAQTVDESLYNVNPYYTDPQALDNFYRIVEANKTGTNWFQEIFSPARIQSHNLSVN
GGSDRANYFFSMSYFDQQGTLNNTYLKRYTIRSNTSYNVTDNIRIGENLTYSISENPTID
NLTEGSAIGMAFRQQPIIPVYDIMGNFAGSFGSGLGNAKNPVAIQERTKNNRGVASRLFG
NVFAEVDFLEHFTARTSFGGQYYSNTYNRFQFPEYENSENLNVNQYTEGSNFNFNYTWTN
TLTYKREFNEQHDLTVLLGTEAYRNNGRNMEAFTQGYFSFDPDYVTLTNGSGTQQHSSSV
YKDALFSLFGRVDYTYNDKYILSATVRRDGSSRFLNEQYGVFPAVSAGWRISEESFMPEN
GWIDDLKLRGGYGQMGNQLNVAPGNAYSTYEGNRNASYYPIDGSNSTIQEGFQEQRIGNP
DAKWERNINSNIGIDASFWQGKVQLTLDYYNKTVDDLLYNPEVIGTQGAAEPPYINIAKM
TNKGFDMDASTYFILAPDLTFTTTLSFTTYSNEIVKIADGVPYFDQEGRRFNGSNIIRNQ
VGHPVSEFFGYQVVGFWNSEQEISDANASAAEATGDAEAVYQDGIGLGRFKYQDTNGDGV
ITPDDRTPLGNPNPKFTYGINLGLEYRNWDFSMFLYGVSGNDIWNNVKWWTDFYSSFQGA
KSHTALYDSWTPENMNATAPIQETTGSFSTAGVPNSYFVENGSYLRARQTQIGYTFNQSF
LDRYHIGGLRLYAQAANLFTITNYSGLDPEISGGTTSFGIDEGQYPNQRQFIFGLNLTF