Protein Info for Echvi_0493 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: TonB-linked outer membrane protein, SusC/RagA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 989 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 29 to 989 (961 residues), 864.5 bits, see alignment E=1.3e-263 PF13620: CarboxypepD_reg" amino acids 30 to 101 (72 residues), 44.5 bits, see alignment 2.5e-15 PF13715: CarbopepD_reg_2" amino acids 31 to 113 (83 residues), 74 bits, see alignment E=1.2e-24 PF07715: Plug" amino acids 121 to 228 (108 residues), 61.9 bits, see alignment E=1.2e-20 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 204 to 234 (31 residues), 65.4 bits, see alignment (E = 2.9e-22)

Best Hits

KEGG orthology group: None (inferred from 56% identity to sli:Slin_6433)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FTZ9 at UniProt or InterPro

Protein Sequence (989 amino acids)

>Echvi_0493 TonB-linked outer membrane protein, SusC/RagA family (Echinicola vietnamensis KMM 6221, DSM 17526)
MKHILLKLAGTLTVFCLCISFSFAQSGGKTVTGVVTNEETGEPIPGATVLEKGTSNGTAT
DLDGNFKLNLTTESPVLTVSFIGYSSKEVSVGNASELSVSLSEDMGQLEEVVVVGYGTQK
RSDITGSVASVPKERLSNLPVTNLTQAIQGTTAGLTVNQGSSVPGSTGGMQIRGVNSINA
NTSPFIVVDGSPYFGTLNDLNANDIESIEILKDASAVAIYGTRGANGVILVTTKRGDQTD
GTPKINYSGYMGFESMSHVLEPMGPDAYVQKYADYLTANNQPQTNILPNASEVENYEAGI
TTDWLDQATQPGRISEHNLSISGGTEKIQYYVSGSHLKQKGVVKGYQYARTNFRTNIDAT
ITNWLKVGTSSFFTDNNYDGGRVNWLEATAMSPYSVPYDENGEYITFPMDPEQLFKNPLL
GLTTDRVDRRRTLSGSGYADITPGFIEGLKYRFNATYVYNFDRFAGYTGRPIYDLNGTAD
VRNTERANWVIENILTYSKDIDKHHFDITALYSAQSVDYFYSSGQSRGFINDALSFNGME
AGTTQATWSDANNYTLLSQMGRLNYAYDSRYLVTLTARRDGYSAFGANTNKYGLFPSMAL
GWNIHNEEFMQDHAGLGELKLRFSYGQSGNQAISPNQTVSTANTVLQPFGGAAQVGVLYN
TLGNADLTWETTTSANLALDFGFVQNRIRGTVEVYKTKTEDILLRRNLPTITGYNSVWAN
LGEMQNKGFELTLNTVNIEKSDFSWETSLNFSTYKNEILDLYGDGRDDIGNRWFIGQPLR
VIFDYEKLGIWQEGEDIASVDPVSQPGDLKFRDQNGDGQITAEDRVVLGQRDPKWVGGLT
NTFRYKNWNLSIFLQTSQGGLKSNRDLTYADEAWRRNLPADYGYWTPDNPSDYWPSLAAY
NRYRGFQFAEDYSYVRIKDVRLSYVVPPSFLERYNIGGLTLYAAGRNLHTFTNWFGWDPE
NTQVSRGSDGWENNYPLVRTISFGLNLTL