Protein Info for Echvi_0402 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: TonB-linked outer membrane protein, SusC/RagA family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1057 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF13620: CarboxypepD_reg" amino acids 32 to 103 (72 residues), 47.5 bits, see alignment 2.9e-16 TIGR04056: TonB-linked outer membrane protein, SusC/RagA family" amino acids 32 to 1057 (1026 residues), 941.5 bits, see alignment E=7.8e-287 PF13715: CarbopepD_reg_2" amino acids 33 to 114 (82 residues), 68.6 bits, see alignment 5.7e-23 PF07715: Plug" amino acids 122 to 258 (137 residues), 58.2 bits, see alignment E=1.7e-19 TIGR04057: TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region" amino acids 234 to 264 (31 residues), 67.7 bits, see alignment (E = 5.8e-23)

Best Hits

KEGG orthology group: None (inferred from 58% identity to sli:Slin_4381)

Predicted SEED Role

"TonB family protein / TonB-dependent receptor" in subsystem Iron acquisition in Vibrio or Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FVJ7 at UniProt or InterPro

Protein Sequence (1057 amino acids)

>Echvi_0402 TonB-linked outer membrane protein, SusC/RagA family (Echinicola vietnamensis KMM 6221, DSM 17526)
MLSIKNRKKILGWGWITLCFAVLSHQLAAQPTVRGRVTDAIEGEPLIGATIVQKGTTNGT
VSDDSGEFSISVPANATLIFSYIGYLSKEVQIGNQTTVDVALEEDLKSLEGVVVVGYGTQ
KKSDLTGAVGTISGKELLSIPSPSFDQMMQGKIAGTQITQTTGAPGGNVNIVIRGVSSIT
GGNQPLYVIDGFAMGAGGSGSDVSSFNGNSFSSGGMAQNTASKINPLTNINPADIESIEI
LKDASATAIYGSRGANGVVIITTKRGKQGQSKINFDASNGVQMIANKLDMLNARQFAEFV
ADGRDNAWVLSGGNASDPNEVRSAGTRVKPEFRNPEAITVNTNWQDVIFRPSVVQSYQLS
ASGGKEGVDYYVSGGYFNQEGIIKGSDFKKFNLRSNIDAYLTKRLKLGISIAGSHSWGKF
ARAEGHLGQRGLISAALASSPALSVYDKNGNYTSELLDPLGVPVENPLLIIDEFSDTRSS
TNVFTNNYLEYEIVEGLTLKSSIGINYIADHTRLWKSSEIGEWGAKTSLATAGVHQRTNL
NWLNENVLNYRRSINGVHDVDAIVGFTAQKDKTDWLQAGATDFPTDHIEYLAGGNVNAGT
NYVSEWSMLSLLARVNYTYKGKYLVTGTVRRDGSSRFGPNNRWGTFPSFSVGYRISEEPF
MQSVTFIDNLKIRASYGVSGNNLIGNYAHIGLLGTTRYVSSNQAALGIIPQSLANENLTW
ERSLQTNIGLDVALFDNRLTLSVDAYKNHKKDLLLNASLPAISGFSASTQNIGELENKGL
EFTLDAVVVNTGNFSWNSNFNIGVNKNKVLVLNSDNARIENSAYQFTEVGRPISSFYMLH
AIGVFQDWDDVDAHPKQHPDVQPGDLKFEDVNGDGVITNDDKTFVGDPWPDYTFGFNNRL
EYDNFALSISVTGSQGNDVYFQGGEIILNAAGVQNQLAVTDERWKSLDDPGNGFTPRAIR
SDYAKGISSNSRYLFDGSYVRIKNINLSYTFQRQTLEKINLSGLSVYGDISNVYTFTDYP
GYDPEASSTGDNIAASGIDYFSYPIPRIFTLGLRVSF