Protein Info for Echvi_0063 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 47 to 67 (21 residues), see Phobius details amino acids 73 to 89 (17 residues), see Phobius details amino acids 101 to 120 (20 residues), see Phobius details amino acids 132 to 152 (21 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 184 to 203 (20 residues), see Phobius details amino acids 214 to 231 (18 residues), see Phobius details amino acids 243 to 266 (24 residues), see Phobius details amino acids 297 to 315 (19 residues), see Phobius details amino acids 321 to 341 (21 residues), see Phobius details PF00953: Glycos_transf_4" amino acids 76 to 229 (154 residues), 149.2 bits, see alignment E=5.1e-48

Best Hits

KEGG orthology group: None (inferred from 43% identity to mtt:Ftrac_2655)

Predicted SEED Role

"Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-)" in subsystem Methicillin resistance in Staphylococci or Teichoic and lipoteichoic acids biosynthesis (EC 2.7.8.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.-

Use Curated BLAST to search for 2.7.8.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FUL1 at UniProt or InterPro

Protein Sequence (384 amino acids)

>Echvi_0063 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase (Echinicola vietnamensis KMM 6221, DSM 17526)
MLLVLFSVLTAFFIGIILTPLLIFLIKKGNLLDKPGGRKIHKYSVPSMGGIAIFIGLLGG
ILIWLNYLQLVEIRFFLLGLSIMFILGLRDDLVELTAYQKLIGQLIAVITVVVLGDVRVS
NFYGLMGVYELPLWFSYSLTIFAIIGLTNAFNLIDGLDGLAGTLSIITFLGLGGWFLYSG
HTTYGFIAFTFVGAVLSFLVYNWHPAKIFMGDTGSLTLGFALSVLCIKFIESNVAIPADS
FKFHAPLATAAALLIVPFYDTLRVFVKRARKGISPMTADKSHVHHFLMRMGFRHDQVAII
LGAVKIGFIVLMVVFNELPDIVMLPTLMVLVVAGGVVLDRLTLRRVKQIVRCSPRVLAQR
SYHGMRAKVKIDEKVLRQEDVNLN