Protein Info for Echvi_0043 in Echinicola vietnamensis KMM 6221, DSM 17526

Annotation: ABC-type antimicrobial peptide transport system, permease component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 transmembrane" amino acids 22 to 46 (25 residues), see Phobius details amino acids 286 to 316 (31 residues), see Phobius details amino acids 336 to 369 (34 residues), see Phobius details amino acids 381 to 404 (24 residues), see Phobius details PF12704: MacB_PCD" amino acids 25 to 225 (201 residues), 106.5 bits, see alignment E=2.4e-34 PF02687: FtsX" amino acids 297 to 408 (112 residues), 53.3 bits, see alignment E=2.8e-18

Best Hits

KEGG orthology group: K02004, (no description) (inferred from 57% identity to mtt:Ftrac_2978)

Predicted SEED Role

"ABC transporter efflux protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0FUB3 at UniProt or InterPro

Protein Sequence (415 amino acids)

>Echvi_0043 ABC-type antimicrobial peptide transport system, permease component (Echinicola vietnamensis KMM 6221, DSM 17526)
MIIFKLIWESFRFALQALRSNLTRTVLSLLGVTIGIFAIIAVFTLVDSLEKNIKSSFSFL
GTNVLRVDRFPFSSGPGEYPWWRYFRRPPANYSEFVFLKERLKNAEAITISASASATLKR
GSSSFEGANLEGVVFDHKEVYDVPVVDGRFFTELEITAARNVTVLGAKIANALFPEGDAI
GKEMKIKGQKFMVIGLLEEEGEGLFDLPSKDDACLIPFGSFGKMYYLGRWGIEPTIAAKG
MDSDRGLIALENEMTGLLRGKRGLKPTEEDDFALNKSEFIQNAIGAIFDVISIAGAVIGG
FSILVGGFGIANIMFVSVRERTNIIGIQKSLGAKNYFILLQFLFESTFLSLFGGLTGLVL
VFAITFIPLGSLEIFMSAKNMALGIGLSMVIGMLSGVVPAGIAARMDPVEAIRTN