Protein Info for EX28DRAFT_4511 in Enterobacter asburiae PDN3

Annotation: Xaa-Pro aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 PF21216: PepQ_N" amino acids 6 to 157 (152 residues), 214.4 bits, see alignment E=7.5e-68 PF00557: Peptidase_M24" amino acids 169 to 430 (262 residues), 143.4 bits, see alignment E=8.6e-46

Best Hits

Swiss-Prot: 94% identical to PEPQ_ENT38: Xaa-Pro dipeptidase (pepQ) from Enterobacter sp. (strain 638)

KEGG orthology group: K01271, Xaa-Pro dipeptidase [EC: 3.4.13.9] (inferred from 98% identity to enc:ECL_04950)

MetaCyc: 89% identical to Xaa-Pro dipeptidase (Escherichia coli K-12 substr. MG1655)
Xaa-Pro dipeptidase. [EC: 3.4.13.9]

Predicted SEED Role

"Xaa-Pro dipeptidase PepQ (EC 3.4.13.9)" (EC 3.4.13.9)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.13.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (443 amino acids)

>EX28DRAFT_4511 Xaa-Pro aminopeptidase (Enterobacter asburiae PDN3)
MDSLASLYKNHIVTLQERTRDVLARFKLDALLIHSGELMNTFLDDHAYPFKVNPQFKAWV
PVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEEIDVIALPKADGIGSQLP
AARGNIAYIGPVPERALGLDIPADKLNPKGVLDYLHYYRAYKTDYELYCMREAQKTAVNG
HRAAHEAFQSGMSEFDINQAYLTATGHRDTDVPYSNIVALNEHASVLHYTKLDHHVPSEM
RSFLLDAGAEYNGYAADLTRTWAANADTEFAQLIKDVNDEQLALIATMKAGTSYVDYHIQ
FHQRIAKLLRKHQIVKDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDTGTHL
AAPSKYPYLRCTRILEPRMVLTIEPGIYFIESLLAPWREGQFSKHFNWEKIDALKPFGGI
RIEDNVVVHENGIENMTRDLKLA