Protein Info for EX28DRAFT_4426 in Enterobacter asburiae PDN3

Annotation: transcriptional regulator, TetR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 212 PF00440: TetR_N" amino acids 23 to 59 (37 residues), 33.8 bits, see alignment 2.3e-12 PF21943: TetR_C_46" amino acids 88 to 187 (100 residues), 46 bits, see alignment E=5.6e-16

Best Hits

Swiss-Prot: 97% identical to FABR_SALAR: HTH-type transcriptional repressor FabR (fabR) from Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)

KEGG orthology group: None (inferred from 100% identity to enc:ECL_05025)

Predicted SEED Role

"Unsaturated fatty acid biosythesis repressor FabR, TetR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (212 amino acids)

>EX28DRAFT_4426 transcriptional regulator, TetR family (Enterobacter asburiae PDN3)
MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELG
LTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAA
FRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVTIVFSAGAEALDVSIEQRKQL
EERLVLQLRMISKGAYYWYRREQEKLAHQTEE