Protein Info for EX28DRAFT_4047 in Enterobacter asburiae PDN3

Annotation: Tetratricopeptide repeat/Cellulose synthase operon protein C C-terminus (BCSC_C)/TPR repeat

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1160 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF13432: TPR_16" amino acids 275 to 337 (63 residues), 24 bits, see alignment 2.2e-08 amino acids 357 to 419 (63 residues), 32.6 bits, see alignment 4.8e-11 amino acids 609 to 670 (62 residues), 17.7 bits, see alignment 2.1e-06 PF13181: TPR_8" amino acids 306 to 336 (31 residues), 23.9 bits, see alignment (E = 1.6e-08) amino acids 392 to 417 (26 residues), 12.1 bits, see alignment (E = 0.0001) PF13176: TPR_7" amino acids 308 to 337 (30 residues), 17.8 bits, see alignment (E = 1.4e-06) PF07719: TPR_2" amino acids 309 to 336 (28 residues), 23.1 bits, see alignment (E = 2.9e-08) PF14559: TPR_19" amino acids 616 to 674 (59 residues), 42.1 bits, see alignment 4.5e-14 PF05420: BCSC_C" amino acids 806 to 1139 (334 residues), 407.4 bits, see alignment E=2.5e-125

Best Hits

Swiss-Prot: 75% identical to BCSC_SALTY: Cellulose synthase operon protein C (bcsC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 94% identity to enc:ECL_04935)

Predicted SEED Role

"Cellulose synthase operon protein C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1160 amino acids)

>EX28DRAFT_4047 Tetratricopeptide repeat/Cellulose synthase operon protein C C-terminus (BCSC_C)/TPR repeat (Enterobacter asburiae PDN3)
MRKFTVNLLTLSLGLALMPMAEAANSPQQKQLLEQVRLGESTQREDLVRQSLYRLELIDP
NNPDVIAARFRYLLRQGDNAGAQKELDRLKGIAPGSSAYQSSRNTMLLSTPDGRQQLQQA
RLLATTGHTQEAIAAYDKLFDGNPPGGDVATEYWNVVAKDPARRNAAINQLKKINASSPG
NTQLQATLSQLLFQSGRRDEGFAVLQEMAKSTNGRSQASDMWYDQIKGQPASSASVSALQ
KYLSVFSSGDSVVAARAQLEEQQKQLADPAFRAKAEGLAAVDAGQGSKAVAELQKAVSAN
HADSEAVGALGQAYSQKGDRARAVAQFEKAIALDPQSDNRGKWDSLLKVNRYWLLIQQGD
AALKANNPAQAERYYQQARSIDNTDSYAVLGLGDAAAARKDNDAAERYYRQALRMDSGNS
NAVRGLANIYRAQSPEKASQFIQSLSASQRRSIDDIERSLTNEQLSAQAEQLENQGKYAQ
AAEIQRRRLALSPGDVWITYRLSRDLYSAGQRSQADTLMRQLASQKPSDPDQVYASGLYL
SGNDQDRAALAHLDTLPRSQWNGNIQELADRLQSNQVLETANRLRDSGKEQEAENLLRQQ
PTSTRIDLTLADWAQQRGDLASAKTTYSAVLQREPQNEDAILGLTEIYSAQGDKDAARAE
LAKLPAAQNGQPLSLNMQRRIAMAQAGLGDSAAAEQTFNNIIPQAKSQPGSMENALVLRD
AARFQAQNGQPQQALETYKDAMVSSGVTTTRPADNDSFTRLTRNDEKDDWLKRGVRSDAG
DLYRQQDVNVTLQHDYWGSSGTGGYSDLKAHTTMLQVDAPLSDGRMFFRSDLVNMDAGSF
DNNNGTYDPKWGTCYETPCSGNTHQSDNGASVAVGWQNKTWAMDIGTTPMGFDVVDVVGG
ISYSSDLGPIGYTVNAHRRPISSSLLAFAGQKDTNTGTTWGGVRATGGGVSMSYDKGEAN
GVWSSLNAETLTGKNVEDNWRVRWMTGYYYKLINKNNERLTVGVSNMLWHYDKDLSGYTL
GQGGYYSPQEYVSFALPVTWRKRTENWSWELGGSVSWSHSKTKDELRYPIQNLIPTDEPD
RYTDRGAMETGSSSSGTGYTARAIIERRVTSNWFVGMGVDIQEAKDYTPSHALIYVRYSA
AGWQGDMDLPPQPLIPYADW