Protein Info for EX28DRAFT_3876 in Enterobacter asburiae PDN3

Annotation: Lipid A core - O-antigen ligase and related enzymes

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 33 to 49 (17 residues), see Phobius details amino acids 57 to 77 (21 residues), see Phobius details amino acids 92 to 110 (19 residues), see Phobius details amino acids 122 to 140 (19 residues), see Phobius details amino acids 153 to 175 (23 residues), see Phobius details amino acids 182 to 198 (17 residues), see Phobius details amino acids 204 to 221 (18 residues), see Phobius details amino acids 228 to 247 (20 residues), see Phobius details amino acids 334 to 354 (21 residues), see Phobius details amino acids 366 to 393 (28 residues), see Phobius details PF04932: Wzy_C" amino acids 189 to 343 (155 residues), 55.6 bits, see alignment E=2.7e-19

Best Hits

KEGG orthology group: K02847, O-antigen ligase [EC: 6.-.-.-] (inferred from 74% identity to enc:ECL_00135)

Predicted SEED Role

"O-antigen ligase" in subsystem LOS core oligosaccharide biosynthesis

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 6.-.-.-

Use Curated BLAST to search for 6.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (404 amino acids)

>EX28DRAFT_3876 Lipid A core - O-antigen ligase and related enzymes (Enterobacter asburiae PDN3)
MEKVKLRLYQLTLILSLISLALALLSSGKQREFFYIAIYASIIGLACEYKKITLRPFSIA
FPILLIGVNNLIWYMVYEYPSEGLNAYSDYLGASKKLILASALVLYLDRFKFYVNEYSFQ
KLFLYFAGIGFVLATVYGLWQASQGMTRIEMAINRATVSAYVYSVLSLAFIYSLFLQKNT
KLYFIAGLTILISWYIILLTGTRAAMGLYLLLAIVLTLYHFRRIHLKSTLIFLCIVAGIA
IVSYKPLISPKITQAQVELEKYQSGVDGTSLGSRFTMWNVGIQNGLKHPLGQSLENRYNW
TQRYVNEGHPNLITALGYLKVHLHNEFIEKYSLQGIPGLAILFFFYISMIAYALKNRNGL
LLTTMLLLLLYGLTDVILLSSEALIFFVTVFALSTPFSQTRQRQ