Protein Info for EX28DRAFT_3832 in Enterobacter asburiae PDN3

Annotation: D-xylose ABC transporter, ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 513 TIGR02633: D-xylose ABC transporter, ATP-binding protein" amino acids 4 to 502 (499 residues), 921.5 bits, see alignment E=1e-281 PF00005: ABC_tran" amino acids 21 to 171 (151 residues), 110.4 bits, see alignment E=1.1e-35 amino acids 277 to 433 (157 residues), 77.3 bits, see alignment E=1.9e-25

Best Hits

Swiss-Prot: 90% identical to XYLG_ECO57: Xylose import ATP-binding protein XylG (xylG) from Escherichia coli O157:H7

KEGG orthology group: K10545, D-xylose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 97% identity to enc:ECL_00199)

MetaCyc: 89% identical to xylose ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-33-RXN [EC: 7.5.2.10, 7.5.2.13]

Predicted SEED Role

"D-xylose transport ATP-binding protein XylG" in subsystem Xylose utilization

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17 or 7.5.2.10 or 7.5.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (513 amino acids)

>EX28DRAFT_3832 D-xylose ABC transporter, ATP-binding protein (Enterobacter asburiae PDN3)
MPYLLEMKSITKRFGMVKAVDNVSLRLNPGEVVSLCGENGSGKSTLMKVLCGIYPHGSYE
GEIVFAGEVIQATHIRDTERKGIAIIHQELALVKHLTVLENIFLGAEISHRGVLDYDTMT
LRCEKLLAQVSLNISPDTRVGDLGLGQQQLVEIAKALNKQVRLLILDEPTASLTEQETAV
LLNIIRDLQNHGIACIYISHKLNEVKAISDTICVIRDGQHIGTREAAGMSEDDIITMMVG
RELTALYPNEPHATGDEVLRVENLTAWHPVNRHIKRVNNVSFALHSGEILGIAGLVGAGR
TEAVQCLFGVWPGRWEGTIYIDGQPVKIDNCQQAIARGIAMVPEDRKKDGIVPVMAVGKN
ITLAALDRFSGALSSLDDAAEQQCILQSLARLKVKTSSPELAIGRLSGGNQQKAILARCL
LLNPRILILDEPTRGIDIGAKYEIYKLINQLVQQGIAVIVISSELPEVLGLSDRVLVMHE
GKLKANLINQNLTQEQVMEAALRSERHVEKQSV