Protein Info for EX28DRAFT_3755 in Enterobacter asburiae PDN3

Annotation: methionine aminopeptidase, type I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00500: methionine aminopeptidase, type I
  • amino acids 3 to 250 (248 residues), 362.7 bits, E=4.8e-113
• PF00557: Peptidase_M24
  • amino acids 12 to 242 (231 residues), 182.2 bits, E=5.7e-58

Best Hits

Swiss-Prot: 92% identical to MAP1_SALTY: Methionine aminopeptidase (map) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01265, methionyl aminopeptidase [EC: 3.4.11.18] (inferred from 100% identity to enc:ECL_00970)

MetaCyc: 90% identical to methionine aminopeptidase (Escherichia coli K-12 substr. MG1655)
Methionyl aminopeptidase. [EC: 3.4.11.18]

Predicted SEED Role

"Methionine aminopeptidase (EC 3.4.11.18)" (EC 3.4.11.18)

MetaCyc Pathways

• Arg/N-end rule pathway (eukaryotic) (4/14 steps found)
• Ac/N-end rule pathway (6/21 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.18

Protein Sequence (264 amino acids)

>EX28DRAFT_3755 methionine aminopeptidase, type I (Enterobacter asburiae PDN3)
MAISIKTPEEIEKMRVAGRLAAEVLEMIEPFVKPGVSTGELDRICNDYIVNEQHAVSACL
GYHGFPKSVCISINEVVCHGIPDDEKLLKDGDIVNIDVTVIKDEYHGDTSKMFIVGKPTI
LGERLCKVTQESLYLALKMVKPGIRLRTIGAAIQKFVEAEGFSVVREYCGHGIGRVFHEE
PQVLHYDADDGGVVLQKGMTFTIEPMVNAGDYRIRTMKDGWTVKTKDRSLSAQYEHTIVV
TDNGCEIMTLRKDDTIPAILTHDE