Protein Info for EX28DRAFT_3196 in Enterobacter asburiae PDN3

Annotation: LppC putative lipoprotein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 720 signal peptide" amino acids 1 to 46 (46 residues), see Phobius details PF04348: LppC" amino acids 40 to 287 (248 residues), 167.4 bits, see alignment E=2.9e-53 amino acids 319 to 714 (396 residues), 275.6 bits, see alignment E=4.9e-86

Best Hits

Swiss-Prot: 87% identical to LPOA_ENT38: Penicillin-binding protein activator LpoA (lpoA) from Enterobacter sp. (strain 638)

KEGG orthology group: K07121, (no description) (inferred from 92% identity to enc:ECL_04529)

Predicted SEED Role

"LppC putative lipoprotein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (720 amino acids)

>EX28DRAFT_3196 LppC putative lipoprotein (Enterobacter asburiae PDN3)
MVPLTFLRKKATRSVPLLLAALIFAGCGTQAPDQSTAHLQGSAQADSGFYLQQMSQSSND
TKTNWQLLAIRALLKEGKTQQAAELFNQLPKDLNDAQRREQSLLSAELKVALKDYAAAKK
ILGDIDVSALDKNQQARFWQAGITAEQGRPSLTLLRALIAQEPLLGGADKQKNIDATWQA
LASMTQEQAQALVINADENVLQGWLDLQQMWFNNRSDPKMLKAGITDWQTRYPQNPGAKM
LPTQLVNVQNFKPASTSKIALLLPLNGQAAVFGRTIQQGFEAAKNGTTSVTGSAVPAQAA
QAANVNDVVSPSAAETSDLTTAQAPAQGTMQNPVTAPTTPPATAAPAAAAPATQAPAETQ
AAPASGTTAEQPQQQTAQPAAQPAAQPQAVATTSANPGAELKIYDTSSQPLDQVLAQVQQ
DGASIVVGPLLKNNVEELMKSNTTLNVLALNQPEQVQNRANICYFALSPEDEARDAARHI
HEQGKQAPLLLIPRSALGDRVANAFADEWQKLGGGVVLQQKFGSVSELRAGVNGGAGIAL
NGSPVTASLPQQQSVTIGGLTIPAPPTDAQISGGGKVDAAYIVATPQEIAFIKPMIAMRN
GSQSGATLYASSRSAQGTAGPDFRLEMDGLQYSEIPMLAGSNPALMQQALSTVRNDYSLA
RLYAMGVDAWALANHFTQMRQVPGFELNGNTGDLTATQDCVINRKLSWLKYQQGQIVPAS