Protein Info for EX28DRAFT_3146 in Enterobacter asburiae PDN3

Annotation: ABC-type sugar transport system, periplasmic component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 333 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF13407: Peripla_BP_4" amino acids 23 to 278 (256 residues), 216.5 bits, see alignment E=2.5e-68

Best Hits

Swiss-Prot: 95% identical to LSRB_ENT38: Autoinducer 2-binding protein LsrB (lsrB) from Enterobacter sp. (strain 638)

KEGG orthology group: K10555, AI-2 transport system substrate-binding protein (inferred from 97% identity to enc:ECL_04479)

MetaCyc: 83% identical to Autoinducer-2 ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-454 [EC: 7.6.2.13]

Predicted SEED Role

"Autoinducer 2 (AI-2) ABC transport system, periplasmic AI-2 binding protein LsrB" in subsystem Autoinducer 2 (AI-2) transport and processing (lsrACDBFGE operon)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (333 amino acids)

>EX28DRAFT_3146 ABC-type sugar transport system, periplasmic component (Enterobacter asburiae PDN3)
MKTKLFVLAMALSFAPAQAADRIAFIPKLVGVGFFTSGGNGAKEAGKELGVDVTYDGPTE
PSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPALKRAMQRGVKVLTWDSDTKPECRSIY
INQGTPEQLGGLLVEMAGKQVTKPNAKVAFFYSSPTVTDQNQWVKEAKAKIEKDHPQWQV
VTTQFGYNDATKSLQTAEGILKAYPDLDAIIAPDANALPAAAQAAENLKREGVAIVGFST
PNVMRPYVERGTVKAFGLWDVVQQGRIAVNVADRLLKKGDLNVGDSVDVKNIGALKVEPN
SVQGYQYEAKGNGIVLLPERVVFTKENISKYDF