Protein Info for EX28DRAFT_2954 in Enterobacter asburiae PDN3

Annotation: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF08659: KR" amino acids 3 to 168 (166 residues), 59.4 bits, see alignment E=6.7e-20 PF00106: adh_short" amino acids 3 to 196 (194 residues), 173.6 bits, see alignment E=5.3e-55 PF13561: adh_short_C2" amino acids 8 to 246 (239 residues), 186.2 bits, see alignment E=1.2e-58

Best Hits

Swiss-Prot: 80% identical to YGFF_ECOLI: Uncharacterized oxidoreductase YgfF (ygfF) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to ent:Ent638_3321)

MetaCyc: 36% identical to lyngbyatoxin A monooxygenase (Moorena producens)
1.14.13.-; 1.14.13.-

Predicted SEED Role

"FIG00553873: hypothetical protein"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (247 amino acids)

>EX28DRAFT_2954 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) (Enterobacter asburiae PDN3)
MAIALVTGASRGIGKATALQLAREGYTVAVNYHHNIKAATDVIKQIVDAGGKAFAVRADI
SDEAQVLAMFDSLDREGEPLRALVNNAGILFEQSTIENLSAERINRVLATNVTGYFLCCR
EAVKRMSFRHGGKGGAIVNVSSAASRLGAPGEYVDYAASKGAVDSLTTGLSLEVAAQGIR
VNCVRPGLIYTDIHASGGEPGRVDRVKSLLPMQRGGQPEEVAQAIVWLLSEKASYVTGSF
LELAGGK