Protein Info for EX28DRAFT_2909 in Enterobacter asburiae PDN3

Annotation: Major Facilitator Superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 397 transmembrane" amino acids 18 to 41 (24 residues), see Phobius details amino acids 53 to 73 (21 residues), see Phobius details amino acids 90 to 117 (28 residues), see Phobius details amino acids 137 to 158 (22 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details amino acids 225 to 245 (21 residues), see Phobius details amino acids 256 to 276 (21 residues), see Phobius details amino acids 285 to 302 (18 residues), see Phobius details amino acids 308 to 330 (23 residues), see Phobius details amino acids 342 to 364 (23 residues), see Phobius details amino acids 371 to 393 (23 residues), see Phobius details PF07690: MFS_1" amino acids 21 to 356 (336 residues), 71.4 bits, see alignment E=3.5e-24

Best Hits

Swiss-Prot: 93% identical to LPLT_ENT38: Lysophospholipid transporter LplT (lplT) from Enterobacter sp. (strain 638)

KEGG orthology group: K08227, MFS transporter, LPLT family, lysophospholipid transporter (inferred from 93% identity to ent:Ent638_3276)

MetaCyc: 87% identical to lysophospholipid transporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-294; TRANS-RXN-295; TRANS-RXN-387

Predicted SEED Role

"Lysophospholipid transporter LplT"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (397 amino acids)

>EX28DRAFT_2909 Major Facilitator Superfamily (Enterobacter asburiae PDN3)
MRESVHTNTSLRSKGMMAVIAAQFLSAFGDNALLFATLALLKAEFYPDWSQPILQMVFVG
AYIIFAPFVGQVADSFPKGRVMMFANGLKLLGAASICFGFNPFIGYSLVGIGAAAYSPAK
YGILGELTTGDKLVKANGLMESSTIAAILLGSVAGGVLADWHVLAALGICAVVYGGAVVA
NLFIPKLPVARPGQSWRFKPMTGSFFTACRVLWRNGETRFSLMGTSMFWGAGVTLRFLLV
LWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVARCMPAGILIGVVVLIFS
LQHALLPAYALLILIGILGGFFVVPLNALLQERGKQTVGAGNAIAVQNLGENLAMLLMLG
LYSLAVKVGVPVVGIGVGFGGLFALAIAGLWVWQRRR