Protein Info for EX28DRAFT_2796 in Enterobacter asburiae PDN3

Annotation: transcriptional regulator, DeoR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 257 PF08279: HTH_11" amino acids 6 to 51 (46 residues), 27.6 bits, see alignment 3.3e-10 PF08220: HTH_DeoR" amino acids 6 to 60 (55 residues), 66.8 bits, see alignment E=1.7e-22 PF00455: DeoRC" amino acids 74 to 231 (158 residues), 176.2 bits, see alignment E=7.8e-56

Best Hits

Swiss-Prot: 91% identical to SRLR_ECOLI: Glucitol operon repressor (srlR) from Escherichia coli (strain K12)

KEGG orthology group: K02468, DeoR family transcriptional regulator, glucitol operon repressor (inferred from 96% identity to enc:ECL_04044)

Predicted SEED Role

"Transcriptional repressor of the fructose operon, DeoR family" in subsystem Fructose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (257 amino acids)

>EX28DRAFT_2796 transcriptional regulator, DeoR family (Enterobacter asburiae PDN3)
MKPRQRQAAILEHLQKQGKCSVEDLAHYFDTTGTTIRKDLVLLENSGAVIRTYGGVVLNK
DEADPPIDHKTLINTHQKALIAEAAVKFIHDGDSIILDAGSTVLQMIPLLSRFNNITVMT
NSLHIVNALSEFDSEQTILMPGGTFRKKSASFHGQLAENAFEHFSFDKLFMGTDGIDLNA
GVTTFNEVFSVSKAMCNAAREVILMADSSKFGRKSPNIVCSLESVDKLITDADIDPAFRK
ALEEKGIDVIVTGERDE