Protein Info for EX28DRAFT_2704 in Enterobacter asburiae PDN3

Annotation: Domain of unknown function (DUF4154)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 198 signal peptide" amino acids 1 to 48 (48 residues), see Phobius details PF13689: DUF4154" amino acids 57 to 193 (137 residues), 106 bits, see alignment E=9.5e-35

Best Hits

Swiss-Prot: 58% identical to YFIR_ECO57: Protein YfiR (yfiR) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 90% identity to enc:ECL_03934)

Predicted SEED Role

"Uncharacterized protein YfiR precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (198 amino acids)

>EX28DRAFT_2704 Domain of unknown function (DUF4154) (Enterobacter asburiae PDN3)
MVFCPQLLRTSISRAMWRILVRNLFLISFFRLTLVLTLFLIVGPAAAGTLTETDKSVRSI
VSGIVSYTRWPSLSGQPKLCVYATSHYTHALSGDEGHSELPYTPVIVRNDREALAATCDA
IYFGSESPAKQLELISQYQGRALLLISEQNPECVIGSAFCLIIDRGQVRFAVNLDALTRS
GVRVNPDVLMLARNKQHG