Protein Info for EX28DRAFT_2628 in Enterobacter asburiae PDN3

Annotation: Aspartate/tyrosine/aromatic aminotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00155: Aminotran_1_2
  • amino acids 34 to 367 (334 residues), 190.9 bits, E=4.1e-60
• PF04864: Alliinase_C
  • amino acids 167 to 277 (111 residues), 29 bits, E=5.2e-11

Best Hits

KEGG orthology group: None (inferred from 52% identity to rce:RC1_0933)

Predicted SEED Role

"Valine--pyruvate aminotransferase (EC 2.6.1.66)" in subsystem Alanine biosynthesis or Branched-Chain Amino Acid Biosynthesis or Pyruvate Alanine Serine Interconversions (EC 2.6.1.66)

MetaCyc Pathways

• superpathway of L-alanine biosynthesis (4/4 steps found)
• L-alanine biosynthesis I (2/2 steps found)

KEGG Metabolic Maps

• Valine, leucine and isoleucine biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 2.6.1.66

Use Curated BLAST to search for 2.6.1.66

Protein Sequence (383 amino acids)

>EX28DRAFT_2628 Aspartate/tyrosine/aromatic aminotransferase (Enterobacter asburiae PDN3)
MKSLSQRSDISPFVVMDVMQAAAEREAHGKIVWHLEVGQPGTSAPAPVIEALKTALPQQT
LGYTVAAGLSALRENISQHYADFYGISVPAENIIVTPGSSAAFILAFLSGFDKGDRVAVP
VPGYPCYRNILLALDLIPVDIHVTAETDYLITARHLRDLTEPVDGIIVSSPNNPTGTMYD
AAVLDELAVYCDSNAITLISDEIYHGITFGTKASSVRQYSEKAIVVNSFSKYFSMTGWRI
GWMIVPDNWLRTVERLIQNLFIATSTLSQVGAIHAFKAYQLMDEYVSGYQQRRDILYAAL
KECGLQNITYPQGAFYIYADVSHLTHDSVAFCKQLLEETGVAITPGVDFDPYNGHKFIRF
SFAADLATITSASEILISWFSRR