Protein Info for EX28DRAFT_2507 in Enterobacter asburiae PDN3

Annotation: ABC-type uncharacterized transport system, permease component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 52 to 77 (26 residues), see Phobius details amino acids 89 to 107 (19 residues), see Phobius details amino acids 176 to 198 (23 residues), see Phobius details amino acids 204 to 231 (28 residues), see Phobius details amino acids 252 to 273 (22 residues), see Phobius details PF03824: NicO" amino acids 14 to 272 (259 residues), 150.2 bits, see alignment E=7.9e-48 PF13386: DsbD_2" amino acids 159 to 241 (83 residues), 29.4 bits, see alignment E=7.2e-11

Best Hits

Swiss-Prot: 64% identical to RCNA_CITK8: Nickel/cobalt efflux system RcnA (rcnA) from Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)

KEGG orthology group: None (inferred from 90% identity to enc:ECL_01222)

MetaCyc: 64% identical to Ni2+/Co2+ exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-584; TRANS-RXN0-585

Predicted SEED Role

"Inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (275 amino acids)

>EX28DRAFT_2507 ABC-type uncharacterized transport system, permease component (Enterobacter asburiae PDN3)
MTDFASLLQQGNAWLFVPSAILLGALHGLEPGHSKTMMAAFIVAIRGTLKQAVLLGLAAT
LSHTAVVWLVAMAGLWFGRGWDAHTSEPWFQLISGVLIVAIALWMAWRTWKESQPHDHHH
HDHDHHHDHHDHDHHHDHHHHEHSLVEEEWQDAHQRAHAQDINRRFSGQNVTTGQIVMFG
LTGGLIPCPASITVLLICLQLKHFALGATLVFSFSIGLALTLVASGAIAALSLRHATKRW
PGFSELSRKAPWISAALITVVGIYMSLHGLSGILA