Protein Info for EX28DRAFT_2238 in Enterobacter asburiae PDN3

Annotation: galactokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 382 TIGR00131: galactokinase" amino acids 5 to 382 (378 residues), 561.4 bits, see alignment E=4.7e-173 PF10509: GalKase_gal_bdg" amino acids 10 to 58 (49 residues), 80.3 bits, see alignment 9.1e-27 PF00288: GHMP_kinases_N" amino acids 114 to 182 (69 residues), 62.2 bits, see alignment E=7.9e-21 PF08544: GHMP_kinases_C" amino acids 279 to 361 (83 residues), 52.3 bits, see alignment E=8.9e-18

Best Hits

Swiss-Prot: 94% identical to GAL1_ENT38: Galactokinase (galK) from Enterobacter sp. (strain 638)

KEGG orthology group: K00849, galactokinase [EC: 2.7.1.6] (inferred from 97% identity to enc:ECL_02980)

MetaCyc: 90% identical to galactokinase (Escherichia coli K-12 substr. MG1655)
Galactokinase. [EC: 2.7.1.6]

Predicted SEED Role

"Galactokinase (EC 2.7.1.6)" in subsystem Lactose and Galactose Uptake and Utilization (EC 2.7.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (382 amino acids)

>EX28DRAFT_2238 galactokinase (Enterobacter asburiae PDN3)
MSLKDKTQSLFAEKFGYPATHVIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAKRD
DRKVRVIAADYGNETDEFSLDAPIVNHDSQQWSNYVRGVVKHLQKRNKNFGGADLVISGN
VPQGAGLSSSASLEVAVGTVFQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISAL
GKKEHALLIDCRSLGTKAVPLPKGAAVVIVNSNFKRTLVGSEYNTRRQQCETGARFFQQP
ALRDVTLNEFNKVAHELDPVVAKRVRHVLTENARTVEAASALAKGDLKRMGELMAESHAS
MRDDFEITVPQIDTLVDIVKATIGDKGGVRMTGGGFGGCIVALVPEELVPAVQDAVAKQY
EAKTGIKETFYVCKASQGAGQC