Protein Info for EX28DRAFT_2012 in Enterobacter asburiae PDN3

Annotation: bacterial condensin subunit MukB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1483 PF04310: MukB" amino acids 2 to 227 (226 residues), 406.9 bits, see alignment E=5.1e-126 PF13555: AAA_29" amino acids 8 to 54 (47 residues), 31.2 bits, see alignment (E = 2.9e-11) PF16330: MukB_hinge" amino acids 645 to 810 (166 residues), 240.7 bits, see alignment E=1.4e-75 PF13558: SbcC_Walker_B" amino acids 1336 to 1424 (89 residues), 48.1 bits, see alignment 2.1e-16

Best Hits

Swiss-Prot: 94% identical to MUKB_ENT38: Chromosome partition protein MukB (mukB) from Enterobacter sp. (strain 638)

KEGG orthology group: K03632, chromosome partition protein MukB (inferred from 92% identity to cro:ROD_09921)

Predicted SEED Role

"Chromosome partition protein MukB" in subsystem DNA structural proteins, bacterial or MukBEF Chromosome Condensation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1483 amino acids)

>EX28DRAFT_2012 bacterial condensin subunit MukB (Enterobacter asburiae PDN3)
MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHF
RNTTEAGATSGSRDKGLHGKLKAGVCYSVLDVINSRHQRVVVGVRLQQVAGRDRKVDIKP
FAIQGLPTSVQPTALLTETLNERQARVLTLQELKDKLEAIEGVQFKQFNSITDYHSLMFD
LGVVARRLRTASDRSKYYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALR
ENRMTLEAIRVTQFDRDLFKHLISEATNYVAADYMRHSNERRVHLDQALEYRRELFTSRK
QLVAEQYKHVEMARELGEHNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDEL
QIRLEEQNEVVAEAADMQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYTQAL
QALQRAKELCHLPDLTPDSADEWLDTFQAKEQEATEKLLSLEQKMSVAQTAHSQFEQAYQ
LVVAINGPLARNEAWDVARELLRDGVNQRHLAEQVQPLRMRLNELEQRLREQQEAERLLA
EFCKRQGKNYDFDELEALHQELEARIAALSDTVSNASEQRMTLRQELEQIQSRSKTLLER
APVWLAAQSSLNQLSEQCGEQFESSQEVTEYLQQLLEREREAIVERDEVGARKLDVDEEI
ERLSQPGGSEDPRLNALAERFGGVLLSEIYDDVGLDDAPYFSALYGPSRNAIVVPDLSLI
SDQLAGLEDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPELPLFGR
AARESRIESLHAERETLSERFATLSFDVQKTQRLHQSFSRFIGSHLAVAFDADPEAEIRK
LNTRRGELERAIASHESDNQQSRVQFEQAKEGVSALNRILPRLNLLADDTLADRVDEIQE
RLDEAQEAARFVQQHGNQLAKLEPVVSVLQSDPEQFEQLKEDYAWSQQVQREARQQAFAL
TEVVQRRAHFGYSDSAEMLSGNSDLNEKLRQRLEQAEAERTRAREAMRSHSAQLNQYNQV
LASLKSSFDTKKELLNDLQKELQDIGVRADSGAEERARIRRDELHSQLSNNRARRNQLEK
ALTFCEAEMDNLTRRLRKLERDYHEMREQVVTAKAGWCAVMRMVKDNNVERRLHRRELAY
LSADELRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQ
DIIRTDDPVEAIEQMEIELGRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRQLNQ
GLQSVSFGQVNSVRLNVNVREAHATLLEVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLN
PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVM
VVQSWEDEARRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLDMQLIIAAPENISP
EKGTTYKLVRKVFQNSEHVHVVGLRGFAPQPPESLPEATADAS