Protein Info for EX28DRAFT_1791 in Enterobacter asburiae PDN3

Annotation: Predicted signal transduction protein containing sensor and EAL domains

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 220 to 243 (24 residues), see Phobius details PF12792: CSS-motif" amino acids 37 to 215 (179 residues), 46.6 bits, see alignment E=2.9e-16 PF00563: EAL" amino acids 254 to 483 (230 residues), 164.2 bits, see alignment E=3.6e-52

Best Hits

KEGG orthology group: None (inferred from 78% identity to enc:ECL_02493)

Predicted SEED Role

"FIG00627129: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (499 amino acids)

>EX28DRAFT_1791 Predicted signal transduction protein containing sensor and EAL domains (Enterobacter asburiae PDN3)
MKKLIAVAIVSTLLVFLSLYAVNAVIIGQQKSKQLEISRTLLHYSEDVSQSVALGLKSIT
AQGCDKTSLDRYRQIKLNNLYFADIGFIDKGKIVCTAFWGKLETPVALPAELHKTPRGFL
LAQFSRKDFFTGNAAIYNNIIIFTSRYAYDKFTPVTASYSLSATTKDFGRVFFSAATELN
QQSWLHSTLFTLTLTQCSTFWDLCVIVKHHDAGLASLPPFIFALLAVILCFIWIAITLFI
FRIYEDRFSLERTLIKAVITNTISVNYQPIIRIHDKKIVGVEVLSRWRDQKHGDVSPELF
IPLIKKIGLYKKYYSNIIEKSLSEIAPLAIKHQLIVSINVGHKEIEDGQFITILRRACFA
NHLPLSLMKVELSEKAVSTADILEGFCQELKSLGVKISIDDFGVQNSNLARLSLLEYDEI
KIDKSLVDGISEHYKQNIFVIFSDALARLNKTLVFEGVENEIQYRFIASRYPDALIQGWY
FSKALTRSELAKRLTGVAP