Protein Info for EX28DRAFT_1790 in Enterobacter asburiae PDN3

Annotation: FOG: EAL domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 transmembrane" amino acids 14 to 36 (23 residues), see Phobius details amino acids 135 to 150 (16 residues), see Phobius details amino acids 231 to 249 (19 residues), see Phobius details PF12792: CSS-motif" amino acids 46 to 230 (185 residues), 50.2 bits, see alignment E=2.3e-17 PF00563: EAL" amino acids 261 to 496 (236 residues), 222.4 bits, see alignment E=6e-70

Best Hits

KEGG orthology group: None (inferred from 58% identity to esc:Entcl_1951)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (516 amino acids)

>EX28DRAFT_1790 FOG: EAL domain (Enterobacter asburiae PDN3)
MLDFSIKENIVRNVMIPILSALFLFLSGILIINWQLWQMAKLSNSHTATASTQKIENILA
EAVSAASTAKRVAAEGCTSSGQLALGTEAALKPHLRAIMIEQQGKIICTSLPGNGVLIIH
PETLPAEKLMLLPGSGLVNGIPVLVFQMPIAGGRVIVSISDAHLQDVIASASNSMDLGLV
VGESMLVRNGAVRGWKAASWKGALTASTQFPFSIAWQPPAFFSLTRLLQQGWSLILLILA
LSVAVGILIRRYKGKSTSFEDDLRKAILQGEIVPYYQPIVNGDTGGLYGVEVLARWKHPK
SGFIPPDVFIPIAERSGLIIPLTKGLMAKVVTQLKPLLPKLPDGFHIGVNISARHINAPS
FIGDCRVFGKGFQGKEVKLVLEVTEREPLIDNPHLVENLNMLHNAGFVIALDDFGTGYSG
LSCLNALAIDYIKIDKSFVNRVSEEKDSTILLDCVIDLAKKLSLRIVAEGVETKEQLEYL
NRNEITLLQGYYFGKPVSYIDFIKVILSKPRETVSL