Protein Info for EX28DRAFT_1789 in Enterobacter asburiae PDN3

Annotation: diguanylate cyclase (GGDEF) domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 490 transmembrane" amino acids 6 to 30 (25 residues), see Phobius details amino acids 171 to 189 (19 residues), see Phobius details amino acids 285 to 306 (22 residues), see Phobius details PF02743: dCache_1" amino acids 31 to 213 (183 residues), 49.2 bits, see alignment E=5e-17 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 320 to 486 (167 residues), 167.2 bits, see alignment E=1.3e-53 PF00990: GGDEF" amino acids 324 to 484 (161 residues), 146.3 bits, see alignment E=7.2e-47

Best Hits

KEGG orthology group: None (inferred from 87% identity to enc:ECL_02492)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (490 amino acids)

>EX28DRAFT_1789 diguanylate cyclase (GGDEF) domain (Enterobacter asburiae PDN3)
MHVKNTFYTTTITVIIVSLIISLSLAVQIATSRQQSIKQINTSVANLSHTLDVYTEGIMR
QSEMLITTVSDIIEIYGMTPQQATNIQRMINNQDNLLTQINNVVVYDAQGDIFTALHETF
TGPRKGSDRSFFIYHKENKNQQIFIGEPVVSRTNGKWVITISRRLETHSGAFNGVVVVTL
GIENFLALYGQINIGHLGVIGLTTQSGVLLVRHPFKNTYVGTIFSDSPLFRKYLKVQNTG
IASSVSRFDKIERIYAYEKNRRYGLVTTVAVSIDEALAPWRKQAIQLALLIFVFTAILIV
ASYFLYSDLSRKTRDNKALKIIASEDALTGLYNRRIFDEKILSEIATCAAHDAAISILIV
DVDYFKKYNDNYGHPEGDRCLALLGNSLRESLIRDNQIVARYGGEEFALILPDTDIQEAL
RLAQTIIRNVFSLQIAHAFSPFGRVTVSVGISTARAVDIAGSQQNIIIAADQALYQAKRA
GRNRYAFVGV