Protein Info for EX28DRAFT_1748 in Enterobacter asburiae PDN3

Annotation: succinylglutamate desuccinylase (EC 3.5.1.96)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 321 TIGR03242: succinylglutamate desuccinylase" amino acids 3 to 317 (315 residues), 428.7 bits, see alignment E=7.6e-133 PF04952: AstE_AspA" amino acids 45 to 319 (275 residues), 248.1 bits, see alignment E=5.9e-78

Best Hits

Swiss-Prot: 64% identical to ASTE_SALPC: Succinylglutamate desuccinylase (astE) from Salmonella paratyphi C (strain RKS4594)

KEGG orthology group: K05526, succinylglutamate desuccinylase [EC: 3.5.1.96] (inferred from 90% identity to enc:ECL_02445)

MetaCyc: 63% identical to succinylglutamate desuccinylase (Escherichia coli K-12 substr. MG1655)
Succinylglutamate desuccinylase. [EC: 3.5.1.96]

Predicted SEED Role

"Succinylglutamate desuccinylase (EC 3.5.1.96)" in subsystem Arginine and Ornithine Degradation (EC 3.5.1.96)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.96

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (321 amino acids)

>EX28DRAFT_1748 succinylglutamate desuccinylase (EC 3.5.1.96) (Enterobacter asburiae PDN3)
MENLLALTLADETPEQKEGDGPSFRWRWLGRGVLELTPTVKSDLSLLLSTGIHGNETAPV
EIVDLLLRALYRNEIALKCRVLVVLGNPPALAQNKRYLVSDINRMFGGRWSQFPQSDETA
RAEWLENVVTAFFATAGPARWHLDLHTAIRASYHVRFGVLPQRSQPWDEAFLSWLGDAGL
EALVFHQSPGGTFTHFTCERFAALACTLELGKALPFGQNDLTRFAPTHLALRALLGGTAP
EHAHQPVERYRVVQQITRRSDAFLLHMAAHTLNFTPFRKGALLAEDGEERYEVQKNTEYV
LFPNPTVAFGLRAGLMLEKIS