Protein Info for EX28DRAFT_1736 in Enterobacter asburiae PDN3

Annotation: Catalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 749 PF00199: Catalase" amino acids 77 to 462 (386 residues), 594.5 bits, see alignment E=1.5e-182 PF06628: Catalase-rel" amino acids 495 to 558 (64 residues), 66.8 bits, see alignment E=2.4e-22 PF18011: Catalase_C" amino acids 595 to 740 (146 residues), 55.6 bits, see alignment E=7.4e-19

Best Hits

Swiss-Prot: 86% identical to CATE_ECOLI: Catalase HPII (katE) from Escherichia coli (strain K12)

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 97% identity to enc:ECL_02433)

MetaCyc: 86% identical to catalase HPII (Escherichia coli K-12 substr. MG1655)
Catalase. [EC: 1.11.1.21, 1.11.1.6]; RXN-8073 [EC: 1.11.1.21, 1.11.1.6]

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.21 or 1.11.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (749 amino acids)

>EX28DRAFT_1736 Catalase (Enterobacter asburiae PDN3)
MSNKDKTHQSPIHGTEESQPGMDSLAPGDGSHRPSPGPSAPGEQPTAPGSMKSPNAENEK
LKSLEPHRKGGEGFALTTNQGVRIADDQNSLRAGARGPTLLEDFILREKITHFDHERIPE
RIVHARGSAAHGYFQPYKSLKAITKADFLSDPDKITPVFVRFSTVQGGAGSADTVRDIRG
FATKFYTEEGIFDLVGNNTPVFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFWDYVS
LQPETLHNVMWAMSDRGIPRSYRTMEGFGIHTFRLINAEGKATFVRFHWKPVAGKASLVW
DEAQKLTGRDPDFHRRELWESIEAGDFPEYELGLQLIPEEDEFKFDFDLLDPTKLIPEEL
VPVQLVGKMVLNRNPDNFFAENEQVAFHPGHIVPGLDFTNDPLLQGRLFSYTDTQISRLG
GPNFHEIPINRPTCPYHNFQRDGMHRQDIDTNPANYEPNSINDNWPRETPPAPKRGGFES
YQERVDGNKIRERSPSFGEYYAHPRLFWNSQTPIEQQHIIGGFSFELSKVVRTYIRERVV
DQLARIDIQLAQSVADNLGITLTDEQRNLAPPKEVNGVKKDPSLSLYAVPGGSIKGRVVA
ILLNDKTRASDVLGIMQALKTQGVHAKLLYSRMGEVTADDGSVLPVAATFAGAPSLTVDA
VIVPCGDIDSLLTNGDAVYYLLEAYKHLKPIALSGDARRFKAQLKVADQGEDGIVEGDNV
DDAFMTKLFDLLAAHRVWSRSSKIDQIPA