Protein Info for EX28DRAFT_1474 in Enterobacter asburiae PDN3

Annotation: AraC-type DNA-binding domain-containing proteins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 116 PF12833: HTH_18" amino acids 27 to 105 (79 residues), 83.8 bits, see alignment E=8.6e-28 PF00165: HTH_AraC" amino acids 69 to 105 (37 residues), 34.4 bits, see alignment E=1.8e-12

Best Hits

Swiss-Prot: 46% identical to MARA_ECO57: Multiple antibiotic resistance protein MarA (marA) from Escherichia coli O157:H7

KEGG orthology group: K05804, right origin-binding protein (inferred from 95% identity to ent:Ent638_1890)

Predicted SEED Role

"Right origin-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (116 amino acids)

>EX28DRAFT_1474 AraC-type DNA-binding domain-containing proteins (Enterobacter asburiae PDN3)
MNTGAFMHDLLDWIDNNLDSRLDIESVARRSGYSKWHLQRLFKEHTGYPLAGYIRAQKLQ
KSVERLTRSDEPILNVAIALGFDSQQSFNRSFKRQYGQAPGAWRRSMAGPETQQLR