Protein Info for EX28DRAFT_1469 in Enterobacter asburiae PDN3

Annotation: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 225 PF00072: Response_reg" amino acids 3 to 113 (111 residues), 83.2 bits, see alignment E=1.5e-27 PF00486: Trans_reg_C" amino acids 147 to 214 (68 residues), 66.4 bits, see alignment E=1.9e-22

Best Hits

Swiss-Prot: 44% identical to BASR_SALTY: Transcriptional regulatory protein BasR (basR) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 91% identity to rah:Rahaq_2332)

Predicted SEED Role

"Two-component system response regulator QseB" in subsystem Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (225 amino acids)

>EX28DRAFT_1469 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain (Enterobacter asburiae PDN3)
MKILLIEDDLDLGNGVRIALSDQGFDVIWVRRKEDALHQLNVCVPELILLDLGLPDGDGM
SLMTRLRQQLKGIPVIILTARGTLQDRLCGLDAGADDYLVKPFILAELLARVRALARRSY
GFENEAIEIRGLSLHVPTRRVTVSARHVDLTASEYALLETLMLRADRVITRRFLEERIFG
NKENLSNALDVHMGNLRRKIGDGYVRTVRGVGYVIDTVSVQKVTG