Protein Info for EX28DRAFT_1407 in Enterobacter asburiae PDN3

Annotation: Beta-lactamase class C and other penicillin binding proteins

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 423 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF00144: Beta-lactamase" amino acids 46 to 374 (329 residues), 170.7 bits, see alignment E=2.4e-54

Best Hits

KEGG orthology group: None (inferred from 62% identity to pva:Pvag_0003)

Predicted SEED Role

"Beta-lactamase (EC 3.5.2.6)" in subsystem Beta-lactamase or Tn552 (EC 3.5.2.6)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.6

Use Curated BLAST to search for 3.5.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (423 amino acids)

>EX28DRAFT_1407 Beta-lactamase class C and other penicillin binding proteins (Enterobacter asburiae PDN3)
MQNITKNIRWLLLTLPLLSGCGTLSQMSSPEGTQELLTHDSLDGDVDSVVRHYMAQKSVP
GMTVAVIHNHGSPQFYTWGVTDAVNRYPVRPDTLFALGSLSKGITAEVVACLVNEGQLNW
NDSLATLLPPGTPLSADAQKITLLELVTHTSGLPRQNMDVPMLGKFISYLSTGDNFYSEL
DSDNVLRSLADWRAPKNKVPQYSNTGYALIGYILKHKTGEDIQSLASRYIFHPLQMANSS
FIPQQLKGYPQRALGHAGDQPKFIPRGQLTPDWHFSNNMVAAASLYSNAEDLAAYARYHV
STTHNPLLDSVFAEVRNTDIQRPDGVQGIAWTTDFIGLEKITYQVGYIGGYSSFIGYDKE
KGNAVVVLQNTFNWSNYIGIALLMDMAKKDSQSPTPPTSALNSHQTSAVFGQAQPRAAAP
PGA