Protein Info for EX28DRAFT_1371 in Enterobacter asburiae PDN3

Annotation: Cyclopropane fatty acid synthase and related methyltransferases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 406 PF02353: CMAS" amino acids 130 to 401 (272 residues), 297 bits, see alignment E=3.9e-92 PF01135: PCMT" amino acids 168 to 306 (139 residues), 22.1 bits, see alignment E=3.4e-08 PF13489: Methyltransf_23" amino acids 175 to 303 (129 residues), 33.7 bits, see alignment E=8.6e-12 PF13649: Methyltransf_25" amino acids 194 to 287 (94 residues), 46.1 bits, see alignment E=2e-15 PF08242: Methyltransf_12" amino acids 194 to 288 (95 residues), 34.5 bits, see alignment E=8.5e-12 PF08241: Methyltransf_11" amino acids 194 to 291 (98 residues), 40 bits, see alignment E=1.6e-13

Best Hits

KEGG orthology group: K00574, cyclopropane-fatty-acyl-phospholipid synthase [EC: 2.1.1.79] (inferred from 93% identity to enc:ECL_02102)

Predicted SEED Role

"Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79), plant type" (EC 2.1.1.79)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.79

Use Curated BLAST to search for 2.1.1.79

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (406 amino acids)

>EX28DRAFT_1371 Cyclopropane fatty acid synthase and related methyltransferases (Enterobacter asburiae PDN3)
MTDPVFALEPDIPRNVRLARWLLFRLLSGIRGGSLTLREGAQTFHFGETSSALHADVQIL
TPGVYWRVLTGGSLAAAEAWMDGEWETAHLTPLLELLALNGEVLGRLENGFRLLGRPLER
IRHWTRRNSRMQARENIAAHYDLGNTFYAHFLDKELLYSSALFTADEQDLTAAQQAKMAR
LCDQLALNPGDHLLEIGTGWGAMAEYAARHYGCRVTTTTLSQEQYTWATERIARAGLQDR
VEVLLCDYRDLTGQYDKLVSIEMIEAVGQRYLPTFFRTCQARLRPGGRMAIQAITIQDQR
YRDYSKSVDFIQRYIFPGGFLPSITAMNELMTRHTDFVVRNLFDMGPDYARTLAHWRQRF
VHAWQEIEKLGFDERFRRMWLYYFGYCEAGFNARTISVVQLTAERV