Protein Info for EX28DRAFT_1341 in Enterobacter asburiae PDN3

Annotation: FOG: EAL domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 487 PF00196: GerE" amino acids 167 to 210 (44 residues), 35.8 bits, see alignment 5e-13 PF00563: EAL" amino acids 243 to 472 (230 residues), 126.9 bits, see alignment E=8.8e-41

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (487 amino acids)

>EX28DRAFT_1341 FOG: EAL domain (Enterobacter asburiae PDN3)
MTHKISLRNEACDEHKFVISACGFTFQGYRLILNQYGIQASHIHFDGDEASQQDLENILI
NQNAHVVVFLGKGIVSLLESLKRLASVLNALPVIRRVTLYGDIPDGWLYRTLGSLLNNSY
QLSLIRIARVSDVVTGFQTHHHVFKDRSYLLRDRYKDNSSQDNVKWLTKREIDVLLNFYR
GMSVKEMCDEMGLSNKTVYTHRKEGVLKLRLIKRWLHDSHNFNAERSIKRRSQNTEFTDK
ETEIFNALYKKEIFPAYQIITDRDKKGVGFEILIRWNKNGKIVKPASFLTDISNHEIWLK
ITALVIHAAVSGINKYNGKYYFSVNIPPRLASGNALPDMAKKAIDMLLKPQWAEKLVFEF
AEDIDVTKDKRIPETMRHLRNTGCRLFLDDCFSNHQTMFPVRQVHFDGLKLDRDIVEHFV
ANDNDYNLIKAIQLYSDMTGTDCIAEGVDSEEKFEKLVALGVKNFQGYYLSRAVKEEELD
RMVRIFS