Protein Info for EX28DRAFT_1254 in Enterobacter asburiae PDN3

Annotation: Transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details PF00126: HTH_1" amino acids 13 to 72 (60 residues), 66.2 bits, see alignment E=2e-22 PF03466: LysR_substrate" amino acids 97 to 305 (209 residues), 131.3 bits, see alignment E=3.3e-42

Best Hits

Swiss-Prot: 81% identical to YDCI_ECOLI: Uncharacterized HTH-type transcriptional regulator YdcI (ydcI) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to enc:ECL_02056)

Predicted SEED Role

"LysR family transcriptional regulator YdcI" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (307 amino acids)

>EX28DRAFT_1254 Transcriptional regulator (Enterobacter asburiae PDN3)
MEKNGLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSKTLNELEQLTGARLFDR
GRLGAQLTIVGEQFLTHAVKVLDALNTAGQSLHRKEEQTSEVVRVGALPTAALGILPPVI
GQFHKQQRHTTIQVATMNNTMLLAGLKSGELDLGIGRMSDPELMGGLNYELLFLESLKLV
VRPDHPLLQDTVTLSRVMEWPVVVCPKGTVPRQTAETLLQMQGCTLPSGCIETLSASLSR
QLTLDYDYVWFVPSGAVKDDLRQGTLIALPITSPGPGEPIGILTRVDTPLSTGAQTLLSA
IRKSMPV