Protein Info for EX28DRAFT_1143 in Enterobacter asburiae PDN3

Annotation: Glycosyltransferases, probably involved in cell wall biogenesis

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 605 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 55 to 79 (25 residues), see Phobius details amino acids 430 to 459 (30 residues), see Phobius details amino acids 471 to 494 (24 residues), see Phobius details amino acids 537 to 559 (23 residues), see Phobius details amino acids 572 to 595 (24 residues), see Phobius details PF13641: Glyco_tranf_2_3" amino acids 111 to 404 (294 residues), 52.3 bits, see alignment E=1.4e-17 PF00535: Glycos_transf_2" amino acids 114 to 303 (190 residues), 52.1 bits, see alignment E=1.6e-17

Best Hits

KEGG orthology group: K00694, cellulose synthase (UDP-forming) [EC: 2.4.1.12] (inferred from 88% identity to kpe:KPK_3080)

Predicted SEED Role

"Cellulose synthase (UDP-forming) (EC 2.4.1.12)" (EC 2.4.1.12)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.12

Use Curated BLAST to search for 2.4.1.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (605 amino acids)

>EX28DRAFT_1143 Glycosyltransferases, probably involved in cell wall biogenesis (Enterobacter asburiae PDN3)
MDFYFSRFEHRRPPEPLKTPRWVMMTWQVLAVAALILGANYIYWRWTASLNTDALWYAIP
LVLAETLAWIGTVLFTINLWKEQDPPQSPPPSEINDCLLSEEAVEPRPVKVDLFIATYSE
DTELVRLSIRDALKMDYPYPIDYRIHVLDDGRRPEMKAVCVEEGVNYISRQTNIGFKAGN
LRNGLEQTDGDFIVICDADTRVFPTLLSHTLGYFRDPDVAWVQTPQWFFDLPEGESLSRW
GKRKAGKVGYGLGWLIQKCVGPVTVGRDPFFNDPRMFYDVILRRRNWANAAFCCGAASIH
RREAVMQAALRSYVWSVEEEIHRHTRDIRDDETRSALQEAMRPHVAFDTELTPYKFHVSE
DIYTSVLLHGDAARRWRSVMHPRVESKMLSPQDMLTWMIQRFKYAAGSLDILFHDNIFSR
RRFRLSLPQTLMYATTFWSYMACVWNTVFLISPIIYLFTGIPPVSAWSTPFYLHFLPFFI
FSELAFMFGTWGISAWDGRASYLSFFSMNLRALNTVLRGEQIKFHVTPKERQTGRFLYLV
KPQIAIVVLTLAGLVWGGIQVARGQVDDPSGYVINIFWGGVNIAAMLPLIFAAMWTPAED
DEVTQ