Protein Info for EX28DRAFT_1082 in Enterobacter asburiae PDN3

Annotation: Permeases of the drug/metabolite transporter (DMT) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 transmembrane" amino acids 29 to 48 (20 residues), see Phobius details amino acids 56 to 75 (20 residues), see Phobius details amino acids 86 to 108 (23 residues), see Phobius details amino acids 115 to 135 (21 residues), see Phobius details amino acids 142 to 160 (19 residues), see Phobius details amino acids 180 to 197 (18 residues), see Phobius details amino acids 207 to 225 (19 residues), see Phobius details amino acids 231 to 255 (25 residues), see Phobius details amino acids 264 to 286 (23 residues), see Phobius details amino acids 292 to 312 (21 residues), see Phobius details PF00892: EamA" amino acids 28 to 159 (132 residues), 30.3 bits, see alignment E=2.3e-11 amino acids 181 to 307 (127 residues), 36.4 bits, see alignment E=3.2e-13

Best Hits

Swiss-Prot: 75% identical to YDDG_SALT1: Methyl viologen resistance protein YddG (yddG) from Salmonella typhimurium (strain 14028s / SGSC 2262)

KEGG orthology group: None (inferred from 86% identity to ent:Ent638_2056)

MetaCyc: 75% identical to amino acid exporter YddG (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-265

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>EX28DRAFT_1082 Permeases of the drug/metabolite transporter (DMT) superfamily (Enterobacter asburiae PDN3)
MGDSVRMNAIHFSFDFYCNGEVMDRKKATLIGLAAILLWSTMVGLIRSVSEGLGPVGGAA
MIYTLSGLLCLVTVGFPDIRRFSPRYLIAGSVLFVSYEICLALSLGYAATRSQAIEVGMV
NYLWPSLTIVFAILFNGQKSTLWVIPGLAVSLLGVCWVLGGEQGLHLDEITRNIVSSPLS
YALAFAGAFIWAAYCTVTSKFAKGQNGITLFVLLTALSLWVKYFLSEQPEMVFTLPVVVK
LVMCGIALGFGYAAWNIGILHGNVTVLAAVSYFTPVLSAALAAAVLSSPLSFSFWQGALM
VCAGSLLCWYATRQ