Protein Info for EX28DRAFT_1011 in Enterobacter asburiae PDN3

Annotation: FOG: EAL domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 507 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details amino acids 218 to 239 (22 residues), see Phobius details PF12792: CSS-motif" amino acids 32 to 217 (186 residues), 77.1 bits, see alignment E=1.4e-25 PF00563: EAL" amino acids 251 to 486 (236 residues), 215.9 bits, see alignment E=5.7e-68

Best Hits

Swiss-Prot: 63% identical to PDEG_ECOLI: Probable cyclic di-GMP phosphodiesterase PdeG (pdeG) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 74% identity to ent:Ent638_1089)

Predicted SEED Role

"Rtn protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (507 amino acids)

>EX28DRAFT_1011 FOG: EAL domain (Enterobacter asburiae PDN3)
MRHASIPVAAATTMFLLGVFIINLQVWYSARADSLAEAHYVVRNMNVILKEARHATEMAM
QLAENECDAEGQYRLGTEAALQPHLRTIVILKNDAVWCSSLPGNRVLLVNSSVLPESSLL
LVPSASTVNGLPVLLYQTIHAGSRIIVSISDSHIRDALDMPLNGVEYSLRVGNTLLGLTG
DVTTADHTKKEVLTVKASNYPFSVQFNSPPLFSLKRLFNRAGGVVLFLLIISSLSAYILQ
RYISKDVSPEESLRIAIYRNEIIPYYQPVVSGKEGTLRGVEVLARWKHPQSGFISPASFI
PLAEKSGLIIPLTQSLMRQVAIHMNAIATLLPEGFHVGINFSASHIVASTFVEECLHYKR
SFTQQDLNLVVEVTEREPLDIDEHLVNTLNVLHNNGFAIALDDFGTGYSGLSYLQDLHID
YIKIDQSFVARVNANEDSTLILDSVLELAKKLSISIVAEGVETEEQLDYLTRNHIRFLQG
FFFYKPLPFKELVKVLLSKPKVKVRVE