Protein Info for EX28DRAFT_0789 in Enterobacter asburiae PDN3

Annotation: type VI secretion system peptidoglycan-associated domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 412 transmembrane" amino acids 201 to 221 (21 residues), see Phobius details TIGR03349: type IV/VI secretion system protein, DotU family" amino acids 20 to 229 (210 residues), 231.2 bits, see alignment E=1.1e-72 PF09850: DotU" amino acids 22 to 223 (202 residues), 235.9 bits, see alignment E=3.5e-74 TIGR03350: type VI secretion system peptidoglycan-associated domain" amino acids 259 to 393 (135 residues), 168.1 bits, see alignment E=9.9e-54 PF00691: OmpA" amino acids 290 to 388 (99 residues), 55.3 bits, see alignment E=7e-19

Best Hits

KEGG orthology group: K11892, type VI secretion system protein ImpK (inferred from 98% identity to enc:ECL_01535)

Predicted SEED Role

"Outer membrane protein ImpK/VasF, OmpA/MotB domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (412 amino acids)

>EX28DRAFT_0789 type VI secretion system peptidoglycan-associated domain (Enterobacter asburiae PDN3)
MQERQDTGSDAGFTGASSNNQLVAAANPLLNAIPQIRHSVSHDDQVALRQRLIDEIRRFE
VRCQQAGLPYEVIVGARYCLCTALDEAAALTPWGSSGVWSSNGLLVTFHNETWGGEKFFQ
LLARLSQNPREHILLLEMINYCLLLGFEGRYRVLDNGRTQLETIKQRLWQMIRGVRGSYP
PPLSPHPEDRPVLRKLWRPMVPLWACVALAGFIACLFYIVLNWRLGDNTNPVLAKIYQSQ
LPETTIQQPARQLPAVLNLRGFLKPEIEAGLVAVKDEADRSVVILKGDGLFASASTVVRD
RYEPVINRIAQAMNNVSGKILVVGYSDNVPIRSARFASNYELSLERARSVQKMLQGSLSQ
PGRVKAEGRGEINPVAPNTTPENRARNRRVEITLLVSPENTQAELNGLPQGN