Protein Info for EX28DRAFT_0763 in Enterobacter asburiae PDN3

Annotation: Na+/H+ antiporter NhaB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 512 transmembrane" amino acids 20 to 79 (60 residues), see Phobius details amino acids 90 to 109 (20 residues), see Phobius details amino acids 120 to 141 (22 residues), see Phobius details amino acids 147 to 165 (19 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details amino acids 238 to 259 (22 residues), see Phobius details amino acids 296 to 315 (20 residues), see Phobius details amino acids 320 to 337 (18 residues), see Phobius details amino acids 349 to 379 (31 residues), see Phobius details amino acids 390 to 412 (23 residues), see Phobius details amino acids 425 to 436 (12 residues), see Phobius details amino acids 451 to 470 (20 residues), see Phobius details amino acids 477 to 503 (27 residues), see Phobius details TIGR00774: Na+/H+ antiporter NhaB" amino acids 1 to 510 (510 residues), 942 bits, see alignment E=5.4e-288 PF06450: NhaB" amino acids 1 to 510 (510 residues), 940 bits, see alignment E=4.2e-287 PF03600: CitMHS" amino acids 71 to 340 (270 residues), 61.6 bits, see alignment E=7.5e-21

Best Hits

Swiss-Prot: 85% identical to NHAB_ENT38: Na(+)/H(+) antiporter NhaB (nhaB) from Enterobacter sp. (strain 638)

KEGG orthology group: K03314, Na+:H+ antiporter, NhaB family (inferred from 94% identity to enc:ECL_01508)

MetaCyc: 83% identical to Na+:H+ antiporter NhaB (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-130

Predicted SEED Role

"Na+/H+ antiporter NhaB" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (512 amino acids)

>EX28DRAFT_0763 Na+/H+ antiporter NhaB (Enterobacter asburiae PDN3)
MEISFGRALWRNFLGQSPDWYKLILLVFLVVNPIIFSVNPFIAGWLLVAEFIFTLAMALK
CYPLLPGGLLAFEAVVIGMTSAEHVKAELASNLEVLLLLIFMVAGIYFMKQLLLFIFTRL
LLSIPSKMFLSLAFCLAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRPNEDLQDD
SHVEAHNRDVLEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGEFFLR
MAPVSVPVLICGLATCLLVEKFSLFGYGAQLPEPVRQELHKFDVQSRSQRTRQETLRLIA
QGIIGVWLIAALAFHLAEVGLIGLSVIILATTFTGVTDEHAIGKAFTEALPFTALLAVFF
AVVAVIIDQHLFAPIIAFVLQASPDAQLSLFYLFNGLLSSISDNVFVGTVYINEAKAAME
QGVISAGQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPY
TLVLTIVGLLCVKITLIPCTQWLVQAGILAAQ