Protein Info for EX28DRAFT_0744 in Enterobacter asburiae PDN3

Annotation: FOG: EAL domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 532 transmembrane" amino acids 16 to 36 (21 residues), see Phobius details amino acids 244 to 263 (20 residues), see Phobius details PF12792: CSS-motif" amino acids 43 to 235 (193 residues), 108.9 bits, see alignment E=2.6e-35 PF00563: EAL" amino acids 275 to 501 (227 residues), 211.4 bits, see alignment E=1.4e-66

Best Hits

Swiss-Prot: 68% identical to PDED_ECOLI: Probable cyclic di-GMP phosphodiesterase PdeD (pdeD) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 86% identity to enc:ECL_01489)

Predicted SEED Role

"Rtn protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (532 amino acids)

>EX28DRAFT_0744 FOG: EAL domain (Enterobacter asburiae PDN3)
MQTAQTIIKNYRRKRVIVCVTVALLTLILTLGIRFISQRNVNQQRILDFTSHTVRALDNV
LLSLENRRSVLQPLVGQPCPQAHLALRKQAAILQTVRSIALINEGILYCSSIFGSRNVPV
RDFLKELPASTAKLILSTDQWLLKDSPILVQWYPVSQEGEAGVIEIINIDLIAKMILEPQ
RPLINDVALTVGDRFLRYGQRVSDSLIFDKEGSLFQQSSTRNPFTITVSGPGPGELALKS
LPAQLPLGLMLSLLLGYLAWLATANRMSFTWEIDMGIAAREFELFCQPLVNARTQACTGV
EILLRWNNPRQGWITPEVFIPLAEEHNQIVPLTRYVIAETVRQIGYFPSSAGFHIGINVA
ASHFRHAVLIQDLNRLWFSASPRQQLVIELTERDALLDADYRIVRELHRKGVKLAIDDFG
TGNSSLSWLEKLHPDVLKIDQSFTTAIGTDAVNSTVTDMIIALGQRLNIELVAEGVETEE
QARYLRRHGVPVLQGFFYARPMPLRDFPKWLAGSASPPAHHNGHIVPLMPLR