Protein Info for EX28DRAFT_0653 in Enterobacter asburiae PDN3

Annotation: ABC-type sugar transport system, ATPase component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 504 PF00005: ABC_tran" amino acids 23 to 172 (150 residues), 117.7 bits, see alignment E=6.2e-38 amino acids 274 to 427 (154 residues), 70.4 bits, see alignment E=2.5e-23

Best Hits

Swiss-Prot: 89% identical to ARAG_SHIDS: Arabinose import ATP-binding protein AraG (araG) from Shigella dysenteriae serotype 1 (strain Sd197)

KEGG orthology group: K10539, L-arabinose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 97% identity to enc:ECL_01395)

MetaCyc: 89% identical to arabinose ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-2-RXN [EC: 7.5.2.12, 7.5.2.13]

Predicted SEED Role

"L-arabinose transport ATP-binding protein AraG (TC 3.A.1.2.2)" in subsystem L-Arabinose utilization (TC 3.A.1.2.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17 or 7.5.2.12 or 7.5.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (504 amino acids)

>EX28DRAFT_0653 ABC-type sugar transport system, ATPase component (Enterobacter asburiae PDN3)
MRQSDPYLSFRGIGKTFPGVNALTDISFDCYAGQVHALMGENGAGKSTLLKILSGNYAPT
TGTLAIRGEEVAFADTTAALNAGVAIIYQELHLIPEMTVAENIYLGQLPHKGGVVNRSLL
NYEAGLQLKHLGLDVDPQTPLKYLSIGQWQMVEIAKALARNARIIAFDEPTSSLSAREIE
NLFRVIRELRQEGRTILYVSHRMEEIFALSDAITVFKDGRYVRTFTDMQQVNHDQLVQAM
VGRELGDIYHWQPRQYGPERLRLDSVKAPGVRTPISLSVRSGEIVGLFGLVGAGRSELMK
GLFGGTRITEGQVSIDGERVDIQKPAHAIRAGMMLCPEDRKAEGIIPVHSVRDNINISAR
RKFIRAGCLINDGWESSNADHHIRSLNIKTPGPEQLIMNLSGGNQQKAILGRWLSEDMKV
ILLDEPTRGIDVGAKHEIYNVIYELAKRGVAVLFASSDLPEVLGVADRIVVMREGEIAGE
LLHEQANEQQALNLAMPKVSQAVA