Protein Info for EX28DRAFT_0448 in Enterobacter asburiae PDN3

Annotation: 2,4-diaminobutyrate 4-transaminases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00709: 2,4-diaminobutyrate 4-transaminase
  • amino acids 18 to 451 (434 residues), 710.5 bits, E=3.3e-218
• PF00202: Aminotran_3
  • amino acids 36 to 449 (414 residues), 339.1 bits, E=1.6e-105

Best Hits

Swiss-Prot: 65% identical to DAT_HAEIN: Diaminobutyrate--2-oxoglutarate aminotransferase (dat) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K00836, diaminobutyrate-2-oxoglutarate transaminase [EC: 2.6.1.76] (inferred from 99% identity to enc:ECL_03421)

MetaCyc: 68% identical to diaminobutyrate--2-oxoglutarate transaminase monomer (Acinetobacter baumannii AYE)
Diaminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.76]

Predicted SEED Role

"Diaminobutyrate--2-oxoglutarate aminotransferase (EC 2.6.1.76)" (EC 2.6.1.76)

MetaCyc Pathways

• norspermidine biosynthesis (4/6 steps found)
• ectoine biosynthesis (3/5 steps found)
• superpathway of polyamine biosynthesis III (4/8 steps found)
• ectoine degradation (1/4 steps found)
• rhizobactin 1021 biosynthesis (2/7 steps found)
• baumannoferrin biosynthesis (2/11 steps found)
• pyoverdine I biosynthesis (2/11 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.76

Protein Sequence (457 amino acids)

>EX28DRAFT_0448 2,4-diaminobutyrate 4-transaminases (Enterobacter asburiae PDN3)
MTDKVRIDTVDAHKSNETYLARQAEFESNVRSYPRKLPLAITKAEGVWITDADNKEYLDC
LAGAGTLALGHNHPDVLKSIQNVITSGLPLHTLDLTTPLKDAFSEYLLSLLPGQGKEYCL
QFTGPSGADAVEAALKLAKKVTGRSGIISFSGGYHGMTHGALSVTGNLSPKEAVDGMMPE
VQFMPYPHEYRCPLGIGGEAGVKALTYYFDNLINDVESGVRKPAAVILEAVQGEGGVNPA
PAEWLQRIRKVTQEHGILLILDEVQAGFARTGKFFAFEHAGIEPDIIVMSKAVGGGLPLA
VLGIKKQFDAWAPGHHTGTFRGNQLAMATGLTTLKILKDQNIAGKVAAQGEWLKGQLKEM
AKRYPVIGHVRGLGMMIGIEIVKPHEAADHMGCFPGDGELSALIQKKCFEAGLILERGGR
NGIVLRLLPSLLISDEELKIFLDKFEQALLAAGVRPA