Protein Info for EX28DRAFT_0445 in Enterobacter asburiae PDN3

Annotation: capsular exopolysaccharide family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 726 transmembrane" amino acids 33 to 52 (20 residues), see Phobius details amino acids 426 to 448 (23 residues), see Phobius details PF02706: Wzz" amino acids 17 to 108 (92 residues), 71.5 bits, see alignment E=1.2e-23 PF13807: GNVR" amino acids 369 to 449 (81 residues), 112 bits, see alignment E=2.1e-36 TIGR01007: capsular exopolysaccharide family" amino acids 514 to 711 (198 residues), 146.7 bits, see alignment E=3.2e-47 PF13614: AAA_31" amino acids 544 to 692 (149 residues), 38.5 bits, see alignment E=2.5e-13

Best Hits

Swiss-Prot: 55% identical to ETK_ECO57: Tyrosine-protein kinase etk (etk) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 68% identity to enc:ECL_03427)

MetaCyc: 55% identical to protein-tyrosine kinase Etk (Escherichia coli K-12 substr. MG1655)
Receptor protein-tyrosine kinase. [EC: 2.7.10.1, 2.7.10.2, 2.7.10.3, 2.7.12.1]

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.1 or 2.7.10.2 or 2.7.10.3 or 2.7.12.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (726 amino acids)

>EX28DRAFT_0445 capsular exopolysaccharide family (Enterobacter asburiae PDN3)
MSSSKSDKYSAATPQNNEIDLLQLFAEMFDNRVTIACVTLLFTVCAGIYAFSATPVYQAD
ALVQVEAKQSNSLLKNLTPFGSELSPDVAPELLLLKSRMILGETVDQLGLTYNARRRVFP
VIGSLWEHVRGRKSDEITIGALTIPLLEGKPQTLLLTVQEKGRYRLEGITLQAEGTVGKT
LVKDGISLLVTSLSAVPGTQFTLETVTRLDAINAIQNRFTVVESAKQSGMIALTLMGEDP
TRIATVLNTIAENFLSQNIARQEAKDSRSLTFLQEQLPKISRELDEAEARLNAYREQRDS
VDLSLEAKSVLDQVVNVENQLNELTFREAEVSQLFKKDHPTYRALREKKQTLERERARLN
NRVSTMPSTQQEILRLSRDVESGRTIYLQLLTRQQELSISRSSTIGNVRIIDPAVVQPEP
IKPRKALIIVLGMLMGLMLSAGMVLVRSAFNRGITSSEQLEVQGIPLLATLPRSVWLWKK
THLRRRTLFASHWKHRTSNVPFLPVDRPADMFVESVRGLCTSLHFTMMDATNRIVVVSGP
TQDCGKTLVSTSLASIAAQAGQRVLFIDADMRKGYVHNVFKLSNHRGLSCVLGGAVEWQE
AVQRVEKGGFDVLTCGPQPLHPVELLMNERFQAVMSQIDKLYDIVIVDTPPVLAVTDALL
IARAAATTLLVARFGKTSVKEIENCLKRLQQMGVQVNGAILNDIVKSAVLYYNSGYSHYD
YGYTQE