Protein Info for EX28DRAFT_0420 in Enterobacter asburiae PDN3

Annotation: PTS system, beta-glucoside-specific IIABC component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 617 transmembrane" amino acids 109 to 138 (30 residues), see Phobius details amino acids 145 to 165 (21 residues), see Phobius details amino acids 172 to 192 (21 residues), see Phobius details amino acids 204 to 228 (25 residues), see Phobius details amino acids 247 to 272 (26 residues), see Phobius details amino acids 283 to 309 (27 residues), see Phobius details amino acids 327 to 347 (21 residues), see Phobius details amino acids 384 to 409 (26 residues), see Phobius details amino acids 429 to 451 (23 residues), see Phobius details TIGR01995: PTS system, beta-glucoside-specific IIABC component" amino acids 3 to 614 (612 residues), 702.8 bits, see alignment E=5.9e-215 PF00367: PTS_EIIB" amino acids 8 to 41 (34 residues), 49.6 bits, see alignment (E = 3.2e-17) PF02378: PTS_EIIC" amino acids 108 to 392 (285 residues), 104.1 bits, see alignment E=1.2e-33 PF00358: PTS_EIIA_1" amino acids 469 to 594 (126 residues), 165.9 bits, see alignment E=5.2e-53 TIGR00830: PTS system, glucose subfamily, IIA component" amino acids 470 to 590 (121 residues), 144.9 bits, see alignment E=1.7e-46

Best Hits

KEGG orthology group: K02755, PTS system, beta-glucosides-specific IIA component [EC: 2.7.1.69] K02756, PTS system, beta-glucosides-specific IIB component [EC: 2.7.1.69] K02757, PTS system, beta-glucosides-specific IIC component (inferred from 90% identity to ent:Ent638_2740)

Predicted SEED Role

"PTS system, beta-glucoside-specific IIB component (EC 2.7.1.69) / PTS system, beta-glucoside-specific IIC component / PTS system, beta-glucoside-specific IIA component" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (617 amino acids)

>EX28DRAFT_0420 PTS system, beta-glucoside-specific IIABC component (Enterobacter asburiae PDN3)
MEYQALAKDILGHVGGKENIVSLVHCATRLRFKLKENQRADAEGLKKNPGVIMVVESGGQ
FQVVIGNHVHDVWQAVRNEAGLTDDAPVVEERGEKGNLLGRLIDIVSGIFTPFIGILAAS
GILKGLLALAVVCGWLTIESGTYKIWFAASDALFFFFPLVLGYTAGKKFGGNPFITMVIG
GALTHPMMIAAFNASQQPGAVSDAFLGIPVTWFNYSSSVIPIILASWVSCWLEKQSTRLL
PSSMKNFFAPLICLGLTVPLTFLAIGPLATWLSQMLANGYQSIYVLAPWLAGAAMGALWQ
VCVIFGLHWGLVPLMINNLAVLGHDSMLPMLLPAVFGQVGAALGIFLRTRDARQKMLAGS
SVTAGIFGITEPAVYGVNLPLRRPFIFGCVAGAIGGAIVGFSDTHVYSFGFANIFTIAQM
IPPGGVNATLWGGVIGTAVALVLSCGLTLAAGMPGRAAPEAAVTAGENDVLSPMSGTVLA
LDQVPDTTFASGLLGSGAAIIPSDNKVVAPFAGVVASLFQTKHAIGLLSTSGIEVLIHVG
IDTVKLDGRPFTAHVKVGDKVQPGDLLLEFDRQAIIDAGYDLATPIIISNSDEYRDVVTV
AATSVNAGAPLLSVSHQ