Protein Info for EX28DRAFT_0398 in Enterobacter asburiae PDN3

Annotation: conserved hypothetical integral membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 37 to 59 (23 residues), see Phobius details amino acids 78 to 97 (20 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 133 to 151 (19 residues), see Phobius details amino acids 162 to 184 (23 residues), see Phobius details amino acids 196 to 214 (19 residues), see Phobius details amino acids 224 to 245 (22 residues), see Phobius details amino acids 263 to 283 (21 residues), see Phobius details amino acids 289 to 312 (24 residues), see Phobius details amino acids 322 to 343 (22 residues), see Phobius details TIGR00698: conserved hypothetical protein" amino acids 13 to 346 (334 residues), 518.7 bits, see alignment E=3.5e-160 PF03601: Cons_hypoth698" amino acids 17 to 325 (309 residues), 387.6 bits, see alignment E=1.6e-120

Best Hits

Swiss-Prot: 88% identical to YEIH_SALTI: UPF0324 inner membrane protein YeiH (yeiH) from Salmonella typhi

KEGG orthology group: None (inferred from 97% identity to enc:ECL_03468)

Predicted SEED Role

"Putative membrane protein YeiH" in subsystem YeiH

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (348 amino acids)

>EX28DRAFT_0398 conserved hypothetical integral membrane protein (Enterobacter asburiae PDN3)
MSEITLQHHRTVWHFVPGLALSAAVTAVALWGGSIPAIAGAGFSALTLAILLGMVVGNTV
YPHIWKSCDGGVIFAKQHLLRLGIILYGFRLTFSQIADVGVSGIAIDVLTLTSTFLLACF
IGQKVFGLDKQTSWLIGAGSSICGAAAVLATEPVVKAETSKVTVAVATVVIFGTLAIFLY
PAMYPLVAHWFSPETYGIYIGSTMHEVAQVVAAGHAINPEAENAAVIAKMLRVMMLAPFL
IFLAARVKQLAPAGGSEKSKITIPWFAILFIVVAIFNSFHLLPKAVVDMLVTLDTVLLAM
AMAALGVTTHVSALKKAGAKPLLMALVLFIWLIVGGGAINLAVHSLMA