Protein Info for EX28DRAFT_0369 in Enterobacter asburiae PDN3

Annotation: Serine protease inhibitor ecotin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 167 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF03974: Ecotin" amino acids 35 to 157 (123 residues), 180 bits, see alignment E=8.1e-58

Best Hits

Swiss-Prot: 77% identical to ECOT_ECO57: Ecotin (eco) from Escherichia coli O157:H7

KEGG orthology group: K08276, ecotin (inferred from 91% identity to enc:ECL_03511)

Predicted SEED Role

"Proteinase inhibitor I11, ecotin precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (167 amino acids)

>EX28DRAFT_0369 Serine protease inhibitor ecotin (Enterobacter asburiae PDN3)
MKNAPKFAIALIAAACVSSSAFASETPKQQPLEKVAPYPQADKGMKRQVIQLPVQQDEAN
FKVELLIGKTLEVDCNQHRLGGQLESKTLEGWGYDYYVFDKVTSPVSTMMACPDGKKEKK
FVTAYLGDNSLLRYNSKLPIVVYTPENVEVKYRIWKADENVGQAVVR