Protein Info for EX28DRAFT_0248 in Enterobacter asburiae PDN3

Annotation: type VI secretion ATPase, ClpV1 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 884 TIGR03345: type VI secretion ATPase, ClpV1 family" amino acids 11 to 864 (854 residues), 1119.9 bits, see alignment E=0 PF13191: AAA_16" amino acids 215 to 316 (102 residues), 33.2 bits, see alignment E=4.6e-11 PF00004: AAA" amino acids 238 to 350 (113 residues), 38 bits, see alignment E=1.4e-12 amino acids 615 to 733 (119 residues), 28.8 bits, see alignment E=9.5e-10 PF17871: AAA_lid_9" amino acids 378 to 469 (92 residues), 110.7 bits, see alignment E=1.9e-35 PF07724: AAA_2" amino acids 610 to 775 (166 residues), 180.4 bits, see alignment E=1.8e-56 PF07728: AAA_5" amino acids 614 to 735 (122 residues), 36.3 bits, see alignment E=3.3e-12 PF10431: ClpB_D2-small" amino acids 781 to 855 (75 residues), 49.7 bits, see alignment E=1.9e-16

Best Hits

KEGG orthology group: K11907, type VI secretion system protein VasG (inferred from 80% identity to eck:EC55989_3334)

Predicted SEED Role

"ClpB protein" in subsystem Protein chaperones or Proteolysis in bacteria, ATP-dependent

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (884 amino acids)

>EX28DRAFT_0248 type VI secretion ATPase, ClpV1 family (Enterobacter asburiae PDN3)
MENPAILLRRLNPYCARAMEGAASLCQTRAHAEILPEHWLLKLLELGEGDLTVLARRYEW
DMDGIWQDLLGWLDRQPRSVRHRPQLSDAIQTLMQEAWMIASLNSEEHIRSVHLLMALVE
KPKLARCDGLWPLLTLAQSQLERLRPLLDAQSDERLEMQREAELTQSHGGEMGFVERPAG
VEMKEGELSPALQNALDKFTLDVTAKAKEGKIDPVFGRDTEIRQMVDILSRRRKNNPILV
GEPGVGKTALVEGLALRIAEGNVPESLKTVTLRTLDLGLLQAGAGVKGEFEQRLKNVIDA
VQQSPVPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFER
DAALERRFQMVKVDEPDDDTACLMLRGLKSRYAEHHNVHITDDAVRAAVTLSRRYLTGRQ
LPDKAVDLLDTAAARVRMSLDTVPEQLTRLRASIAALDMEKQALLEDIAIGNQCHAERLC
EIEQEEVRQIVTLDELETQYGHEMKLAEQLRESRQDISRQRETHRLQQELNEMQRSNPLL
SLDVDVRTVANVIADWTGVPLSSLMKDEQTELLALENEIGKRVVGQDVALEAIARRLRAA
KTGLTSENGPQGVFLLVGPSGVGKTETALALADVMYGGEKSLITINLSEYQEPHTVSQLK
GSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGFMRDGEGREI
DFRNTVILMTSNLGSDHLMQLLDENPEATEADLHELLRPILRDHFQPALLARFQTVIYRP
LAEAAMRTIVEMKLSQVSKRLHRHYGLTMQIDESLNDALTAACLLPDTGARNVDSLLNQQ
ILPVLSQQLLTHMAARQKPASLSLSWSEEEGIGLEFNRIQGVNA