Protein Info for EX28DRAFT_0244 in Enterobacter asburiae PDN3

Annotation: type VI secretion protein, VC_A0114 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 TIGR03353: type VI secretion protein, VC_A0114 family" amino acids 6 to 444 (439 residues), 421.8 bits, see alignment E=1.5e-130 PF05936: T6SS_VasE" amino acids 18 to 443 (426 residues), 445.5 bits, see alignment E=9.3e-138

Best Hits

KEGG orthology group: K11893, type VI secretion system protein ImpJ (inferred from 89% identity to pam:PANA_4149)

Predicted SEED Role

"Uncharacterized protein ImpJ/VasE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (446 amino acids)

>EX28DRAFT_0244 type VI secretion protein, VC_A0114 family (Enterobacter asburiae PDN3)
MKTEQPLWGRGIMVSPQHFQQQVAYAAWSAECIARLGLSCPWGVIKATFEPEALRLGRLQ
AHHLHVRFQDGTLIDTDNADTLPPVLSLERESQEVTVVLALPLLRSNGGNCLKPEEVAER
PVRYRQRWRDVRNAYGDDTRQIAVMQPELTLRFAHQNNSDYLICPVARLQQDSQGTWQLD
ETFLPPLLTLQGSRWLVTQLEQLMTQLRARLCRLMAMRRESNERMADFAVADVSLFWLLN
ALNSAEPVLGQFQRNLQSPPERLYPELSRLAGSLLTFSLEHQVSAIPIWHHEQLNMVFPP
LFDLLGDLLEASLPSRVVALSLDYDPRLHFWQARLHDPRLREGADYYLSVRSPIPVAQLQ
EQFPRQCKVGSPDHVRGIVNSSRVGVPLMPLRHVPAAIPLRLENQYFSLDLSHPLATEML
QSGTCMFYVPGMLGEPELELFAVLRT